Identification of key genes by integrating DNA methylation and next-generation transcriptome sequencing for esophageal squamous cell carcinoma.

Chen, Yang; Liao, Lian-Di; Wu, Zhi-Yong; Yang, Qian; Guo, Jin-Cheng; He, Jian-Zhong; Wang, Shao-Hong; Xu, Xiu-E; Wu, Jian-Yi; Pan, Feng; Lin, De-Chen; Xu, Li-Yan; Li, En-Min

Chen, Yang; Liao, Lian-Di; Wu, Zhi-Yong; Yang, Qian; Guo, Jin-Cheng; He, Jian-Zhong; Wang, Shao-Hong; Xu, Xiu-E; Wu, Jian-Yi; Pan, Feng; Lin, De-Chen; Xu, Li-Yan; Li, En-Min.

Afiliação

Chen Y; The Key Laboratory of Molecular Biology for High Cancer Incidence Coastal Chaoshan Area, Shantou University Medical College, Shantou 515041, Guangdong, P.R. China.
Liao LD; Department of Biochemistry and Molecular Biology, Shantou University Medical College, Shantou 515041, Guangdong, P.R. China.
Wu ZY; The Key Laboratory of Molecular Biology for High Cancer Incidence Coastal Chaoshan Area, Shantou University Medical College, Shantou 515041, Guangdong, P.R. China.
Yang Q; Institute of Oncologic Pathology, Shantou University Medical College, Shantou 515041, Guangdong, P.R. China.
Guo JC; Departments of Oncology Surgery, Shantou Central Hospital, Affiliated Shantou Hospital of Sun Yat-Sen University, Shantou 515041, Guangdong, P.R. China.
He JZ; The Key Laboratory of Molecular Biology for High Cancer Incidence Coastal Chaoshan Area, Shantou University Medical College, Shantou 515041, Guangdong, P.R. China.
Wang SH; Department of Biochemistry and Molecular Biology, Shantou University Medical College, Shantou 515041, Guangdong, P.R. China.
Xu XE; The Key Laboratory of Molecular Biology for High Cancer Incidence Coastal Chaoshan Area, Shantou University Medical College, Shantou 515041, Guangdong, P.R. China.
Wu JY; Department of Biochemistry and Molecular Biology, Shantou University Medical College, Shantou 515041, Guangdong, P.R. China.
Pan F; The Key Laboratory of Molecular Biology for High Cancer Incidence Coastal Chaoshan Area, Shantou University Medical College, Shantou 515041, Guangdong, P.R. China.
Lin DC; Institute of Oncologic Pathology, Shantou University Medical College, Shantou 515041, Guangdong, P.R. China.
Xu LY; Departments of Pathology, Shantou Central Hospital, Affiliated Shantou Hospital of Sun Yat-Sen University, Shantou 515041, Guangdong, P.R. China.
Li EM; The Key Laboratory of Molecular Biology for High Cancer Incidence Coastal Chaoshan Area, Shantou University Medical College, Shantou 515041, Guangdong, P.R. China.

Aging (Albany NY) ; 12(2): 1332-1365, 2020 01 21.

Article em En | MEDLINE | ID: mdl-31962291

Assuntos

Metilação de DNA; Neoplasias Esofágicas/genética; Carcinoma de Células Escamosas do Esôfago/genética; Perfilação da Expressão Gênica; Regulação Neoplásica da Expressão Gênica; Transcriptoma; Biomarcadores Tumorais; Biologia Computacional/métodos; Neoplasias Esofágicas/metabolismo; Neoplasias Esofágicas/mortalidade; Carcinoma de Células Escamosas do Esôfago/metabolismo; Carcinoma de Células Escamosas do Esôfago/mortalidade; Feminino; Sequenciamento de Nucleotídeos em Larga Escala; Histonas/metabolismo; Humanos; Estimativa de Kaplan-Meier; Masculino; Prognóstico; Análise de Sequência de DNA

Palavras-chave

DNA methylation; esophageal squamous cell carcinoma; histone modification; next-generation sequencing; survival analysis

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Neoplasias Esofágicas / Regulação Neoplásica da Expressão Gênica / Metilação de DNA / Perfilação da Expressão Gênica / Transcriptoma / Carcinoma de Células Escamosas do Esôfago Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Female / Humans / Male Idioma: En Revista: Aging (Albany NY) Assunto da revista: GERIATRIA Ano de publicação: 2020 Tipo de documento: Article

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