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mTORC1 directly inhibits AMPK to promote cell proliferation under nutrient stress.
Ling, Naomi X Y; Kaczmarek, Adrian; Hoque, Ashfaqul; Davie, Elizabeth; Ngoei, Kevin R W; Morrison, Kaitlin R; Smiles, William J; Forte, Gabriella M; Wang, Tingting; Lie, Shervi; Dite, Toby A; Langendorf, Christopher G; Scott, John W; Oakhill, Jonathan S; Petersen, Janni.
Afiliação
  • Ling NXY; Metabolic Signalling Laboratory, St Vincent's Institute of Medical Research, School of Medicine, University of Melbourne, Melbourne, Victoria, Australia.
  • Kaczmarek A; Flinders Centre for Innovation in Cancer, College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia.
  • Hoque A; Metabolic Signalling Laboratory, St Vincent's Institute of Medical Research, School of Medicine, University of Melbourne, Melbourne, Victoria, Australia.
  • Davie E; Faculty of Life Sciences, University of Manchester, Manchester, UK.
  • Ngoei KRW; Protein Chemistry and Metabolism Unit, St Vincent's Institute of Medical Research, School of Medicine, University of Melbourne, Melbourne, Victoria, Australia.
  • Morrison KR; Flinders Centre for Innovation in Cancer, College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia.
  • Smiles WJ; Metabolic Signalling Laboratory, St Vincent's Institute of Medical Research, School of Medicine, University of Melbourne, Melbourne, Victoria, Australia.
  • Forte GM; Faculty of Life Sciences, University of Manchester, Manchester, UK.
  • Wang T; Flinders Centre for Innovation in Cancer, College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia.
  • Lie S; Flinders Centre for Innovation in Cancer, College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia.
  • Dite TA; Metabolic Signalling Laboratory, St Vincent's Institute of Medical Research, School of Medicine, University of Melbourne, Melbourne, Victoria, Australia.
  • Langendorf CG; MRC Protein Phosphorylation and Ubiquitylation Unit, James Black Centre, University of Dundee, Dundee, UK.
  • Scott JW; Protein Chemistry and Metabolism Unit, St Vincent's Institute of Medical Research, School of Medicine, University of Melbourne, Melbourne, Victoria, Australia.
  • Oakhill JS; Protein Chemistry and Metabolism Unit, St Vincent's Institute of Medical Research, School of Medicine, University of Melbourne, Melbourne, Victoria, Australia.
  • Petersen J; Mary MacKillop Institute for Health Research, Australian Catholic University, Melbourne, Victoria, Australia.
Nat Metab ; 2(1): 41-49, 2020 01.
Article em En | MEDLINE | ID: mdl-31993556
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Estresse Fisiológico / Nutrientes / Adenilato Quinase / Proliferação de Células / Alvo Mecanístico do Complexo 1 de Rapamicina Limite: Humans Idioma: En Revista: Nat Metab Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Austrália
Texto completo
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XML
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Estresse Fisiológico / Nutrientes / Adenilato Quinase / Proliferação de Células / Alvo Mecanístico do Complexo 1 de Rapamicina Limite: Humans Idioma: En Revista: Nat Metab Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Austrália