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Preclinical Optimization of gp120 Entry Antagonists as anti-HIV-1 Agents with Improved Cytotoxicity and ADME Properties through Rational Design, Synthesis, and Antiviral Evaluation.
Curreli, Francesca; Ahmed, Shahad; Benedict Victor, Sofia M; Iusupov, Ildar R; Belov, Dmitry S; Markov, Pavel O; Kurkin, Alexander V; Altieri, Andrea; Debnath, Asim K.
Afiliação
  • Curreli F; Laboratory of Molecular Modeling & Drug Design, Lindsley F. Kimball Research Institute , New York Blood Center , 310 E 67th Street , New York 10065 , New York , United States.
  • Ahmed S; Laboratory of Molecular Modeling & Drug Design, Lindsley F. Kimball Research Institute , New York Blood Center , 310 E 67th Street , New York 10065 , New York , United States.
  • Benedict Victor SM; Laboratory of Molecular Modeling & Drug Design, Lindsley F. Kimball Research Institute , New York Blood Center , 310 E 67th Street , New York 10065 , New York , United States.
  • Iusupov IR; EDASA Scientific, Scientific Park , Moscow State University , Leninskie Gory Bld. 75, 77-101b , Moscow 119992 , Russia.
  • Belov DS; EDASA Scientific, Scientific Park , Moscow State University , Leninskie Gory Bld. 75, 77-101b , Moscow 119992 , Russia.
  • Markov PO; EDASA Scientific, Scientific Park , Moscow State University , Leninskie Gory Bld. 75, 77-101b , Moscow 119992 , Russia.
  • Kurkin AV; EDASA Scientific, Scientific Park , Moscow State University , Leninskie Gory Bld. 75, 77-101b , Moscow 119992 , Russia.
  • Altieri A; EDASA Scientific, Scientific Park , Moscow State University , Leninskie Gory Bld. 75, 77-101b , Moscow 119992 , Russia.
  • Debnath AK; Laboratory of Molecular Modeling & Drug Design, Lindsley F. Kimball Research Institute , New York Blood Center , 310 E 67th Street , New York 10065 , New York , United States.
J Med Chem ; 63(4): 1724-1749, 2020 02 27.
Article em En | MEDLINE | ID: mdl-32031803
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Piridinas / Pirróis / Tiazóis / Proteína gp120 do Envelope de HIV / Fármacos Anti-HIV Limite: Humans Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Piridinas / Pirróis / Tiazóis / Proteína gp120 do Envelope de HIV / Fármacos Anti-HIV Limite: Humans Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos