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Structure of CD20 in complex with the therapeutic monoclonal antibody rituximab.
Rougé, Lionel; Chiang, Nancy; Steffek, Micah; Kugel, Christine; Croll, Tristan I; Tam, Christine; Estevez, Alberto; Arthur, Christopher P; Koth, Christopher M; Ciferri, Claudio; Kraft, Edward; Payandeh, Jian; Nakamura, Gerald; Koerber, James T; Rohou, Alexis.
Afiliação
  • Rougé L; Department of Structural Biology, Genentech Inc., South San Francisco, CA 94080, USA.
  • Chiang N; Department of Antibody Engineering, Genentech Inc., South San Francisco, CA 94080, USA.
  • Steffek M; Department of Biochemical and Cellular Pharmacology, Genentech Inc., South San Francisco, CA 94080, USA.
  • Kugel C; Department of Biomolecular Resources, Genentech Inc., South San Francisco, CA 94080, USA.
  • Croll TI; Cambridge Institute for Medical Research, University of Cambridge, Keith Peters Building, Cambridge CB2 0XY, UK.
  • Tam C; Department of Biomolecular Resources, Genentech Inc., South San Francisco, CA 94080, USA.
  • Estevez A; Department of Structural Biology, Genentech Inc., South San Francisco, CA 94080, USA.
  • Arthur CP; Department of Structural Biology, Genentech Inc., South San Francisco, CA 94080, USA.
  • Koth CM; Department of Structural Biology, Genentech Inc., South San Francisco, CA 94080, USA.
  • Ciferri C; Department of Structural Biology, Genentech Inc., South San Francisco, CA 94080, USA.
  • Kraft E; Department of Biomolecular Resources, Genentech Inc., South San Francisco, CA 94080, USA.
  • Payandeh J; Department of Structural Biology, Genentech Inc., South San Francisco, CA 94080, USA. rohou.alexis@gene.com koerber.james@gene.com nakamura.gerald@gene.com payandeh.jian@gene.com.
  • Nakamura G; Department of Antibody Engineering, Genentech Inc., South San Francisco, CA 94080, USA.
  • Koerber JT; Department of Antibody Engineering, Genentech Inc., South San Francisco, CA 94080, USA. rohou.alexis@gene.com koerber.james@gene.com nakamura.gerald@gene.com payandeh.jian@gene.com.
  • Rohou A; Department of Antibody Engineering, Genentech Inc., South San Francisco, CA 94080, USA. rohou.alexis@gene.com koerber.james@gene.com nakamura.gerald@gene.com payandeh.jian@gene.com.
Science ; 367(6483): 1224-1230, 2020 03 13.
Article em En | MEDLINE | ID: mdl-32079680

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Antígenos CD20 / Rituximab Limite: Humans Idioma: En Revista: Science Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Antígenos CD20 / Rituximab Limite: Humans Idioma: En Revista: Science Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos