Impact of attenuation correction for CZT-SPECT measurement of myocardial blood flow.
J Nucl Cardiol
; 28(6): 2560-2568, 2021 12.
Article
em En
| MEDLINE
| ID: mdl-32080802
ABSTRACT
OBJECTIVES:
Most of cardiac dedicated CZT-SPECT systems are not equipped with CT, whereas PET systems are. We evaluated the impact of AC correction on CZT-SPECT myocardial blood flow (MBF) and myocardial flow reserve (MFR) measurements.METHODS:
104 patients were included. SPECT data were acquired on cadmium zinc telluride (CZT)-based pinhole cardiac camera in listmode using a stress (250 ± 17 MBq)/rest (511 ± 23 MBq) 1-day Tc-99m-tetrofosmin protocol. Low-dose CT was acquired on another SPECT/CT camera in the same position. All analysis was performed using Corridor4DM.RESULTS:
Stress and rest MBF were significantly lower when AC was applied (P < 0.001). For regional and global MFR, there was no significant difference between AC and NAC measurements (P > 0.25 at least). Mean global LV MFR was 2.43 ± 0.87 and 2.33 ± 0.89, respectively, for NAC and AC measurements. Using a threshold of 2, 86 patients (83%) remained classified as normal and abnormal regarding global LV MFR whether AC was applied or not. Mean difference between NAC and AC values for the 18 other patients was 0.3.CONCLUSION:
AC correction does not significantly affect MFR measurement both in regional and global LV analyses.Palavras-chave
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Telúrio
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Zinco
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Cádmio
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Tomografia Computadorizada de Emissão de Fóton Único
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Circulação Coronária
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Imagem de Perfusão do Miocárdio
Limite:
Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
J Nucl Cardiol
Assunto da revista:
CARDIOLOGIA
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
França