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Combining mutagenesis on Glu281 of prenyltransferase NovQ and metabolic engineering strategies for the increased prenylated activity towards menadione.
Ni, Wenfeng; Zheng, Zhiming; Liu, Hui; Wang, Peng; Wang, Han; Sun, Xiaowen; Yang, Qiang; Fang, Zhiwei; Tang, Hengfang; Zhao, Genhai.
Afiliação
  • Ni W; Key Laboratory of High Magnetic Field and Ion Beam Physical Biology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, 350 Shushanhu Road, Hefei, 230031, Anhui, People's Republic of China.
  • Zheng Z; University of Science and Technology of China, Hefei, 230026, Anhui, People's Republic of China.
  • Liu H; Key Laboratory of High Magnetic Field and Ion Beam Physical Biology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, 350 Shushanhu Road, Hefei, 230031, Anhui, People's Republic of China. zhengzhiming2014@163.com.
  • Wang P; Key Laboratory of High Magnetic Field and Ion Beam Physical Biology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, 350 Shushanhu Road, Hefei, 230031, Anhui, People's Republic of China.
  • Wang H; Key Laboratory of High Magnetic Field and Ion Beam Physical Biology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, 350 Shushanhu Road, Hefei, 230031, Anhui, People's Republic of China.
  • Sun X; Key Laboratory of High Magnetic Field and Ion Beam Physical Biology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, 350 Shushanhu Road, Hefei, 230031, Anhui, People's Republic of China.
  • Yang Q; University of Science and Technology of China, Hefei, 230026, Anhui, People's Republic of China.
  • Fang Z; Key Laboratory of High Magnetic Field and Ion Beam Physical Biology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, 350 Shushanhu Road, Hefei, 230031, Anhui, People's Republic of China.
  • Tang H; University of Science and Technology of China, Hefei, 230026, Anhui, People's Republic of China.
  • Zhao G; Key Laboratory of High Magnetic Field and Ion Beam Physical Biology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, 350 Shushanhu Road, Hefei, 230031, Anhui, People's Republic of China.
Appl Microbiol Biotechnol ; 104(10): 4371-4382, 2020 May.
Article em En | MEDLINE | ID: mdl-32125480
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Streptomyces / Proteínas de Bactérias / Vitaminas / Mutagênese / Vitamina K 3 / Dimetilaliltranstransferase / Engenharia Metabólica Idioma: En Revista: Appl Microbiol Biotechnol Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Adicionar na Minha BVS
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XML
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Streptomyces / Proteínas de Bactérias / Vitaminas / Mutagênese / Vitamina K 3 / Dimetilaliltranstransferase / Engenharia Metabólica Idioma: En Revista: Appl Microbiol Biotechnol Ano de publicação: 2020 Tipo de documento: Article