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HNF1A recruits KDM6A to activate differentiated acinar cell programs that suppress pancreatic cancer.
Kalisz, Mark; Bernardo, Edgar; Beucher, Anthony; Maestro, Miguel Angel; Del Pozo, Natalia; Millán, Irene; Haeberle, Lena; Schlensog, Martin; Safi, Sami Alexander; Knoefel, Wolfram Trudo; Grau, Vanessa; de Vas, Matías; Shpargel, Karl B; Vaquero, Eva; Magnuson, Terry; Ortega, Sagrario; Esposito, Irene; Real, Francisco X; Ferrer, Jorge.
Afiliação
  • Kalisz M; Section of Epigenomics and Disease, Department of Medicine, Imperial College London, London, UK.
  • Bernardo E; Epithelial Carcinogenesis Group, Spanish National Cancer Research Centre-CNIO, Madrid, Spain.
  • Beucher A; CIBERONC, Madrid, Spain.
  • Maestro MA; Bioinformatics and Genomics Program, Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.
  • Del Pozo N; Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Barcelona, Spain.
  • Millán I; Section of Epigenomics and Disease, Department of Medicine, Imperial College London, London, UK.
  • Haeberle L; Bioinformatics and Genomics Program, Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.
  • Schlensog M; Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Barcelona, Spain.
  • Safi SA; Epithelial Carcinogenesis Group, Spanish National Cancer Research Centre-CNIO, Madrid, Spain.
  • Knoefel WT; CIBERONC, Madrid, Spain.
  • Grau V; Epithelial Carcinogenesis Group, Spanish National Cancer Research Centre-CNIO, Madrid, Spain.
  • de Vas M; CIBERONC, Madrid, Spain.
  • Shpargel KB; Institute of Pathology, Heinrich-Heine University and University Hospital of Düsseldorf, Düsseldorf, Germany.
  • Vaquero E; Institute of Pathology, Heinrich-Heine University and University Hospital of Düsseldorf, Düsseldorf, Germany.
  • Magnuson T; Department of Surgery, Heinrich-Heine University and University Hospital of Düsseldorf, Düsseldorf, Germany.
  • Ortega S; Department of Surgery, Heinrich-Heine University and University Hospital of Düsseldorf, Düsseldorf, Germany.
  • Esposito I; Bioinformatics and Genomics Program, Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.
  • Real FX; Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Barcelona, Spain.
  • Ferrer J; Section of Epigenomics and Disease, Department of Medicine, Imperial College London, London, UK.
EMBO J ; 39(9): e102808, 2020 05 04.
Article em En | MEDLINE | ID: mdl-32154941
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Carcinoma Ductal Pancreático / Fator 1-alfa Nuclear de Hepatócito / Histona Desmetilases / Células Acinares Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: EMBO J Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Carcinoma Ductal Pancreático / Fator 1-alfa Nuclear de Hepatócito / Histona Desmetilases / Células Acinares Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: EMBO J Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Reino Unido