A Tuft Act to Follow: Leukotrienes Take the Stage in Anti-worm Immunity.

Fung, Connie; Howitt, Michael R

Fung, Connie; Howitt, Michael R.

Afiliação

Fung C; Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Howitt MR; Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address: mhowitt@stanford.edu.

Immunity ; 52(3): 426-428, 2020 03 17.

Article em En | MEDLINE | ID: mdl-32187512

ABSTRACT

ABSTRACT

Tuft cells are specialized taste-chemosensory cells that detect the presence of intestinal parasites and orchestrate type 2 immunity. In this issue of Immunity, McGinty et al. discover that parasitic worms, but not commensal protists, stimulate tuft cells to release cysteinyl leukotrienes to amplify anti-helminth immunity in the small intestine.

Assuntos

Helmintos; Mebendazol; Animais; Mucosa Intestinal; Intestino Delgado; Leucotrienos

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Helmintos / Mebendazol Limite: Animals Idioma: En Revista: Immunity Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos

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