Biomimetic mineralization of nanocrystalline hydroxyapatites on aminated modified polylactic acid microspheres to develop a novel drug delivery system for alendronate.

Chen, Shunyu; Guo, Rongying; Xie, Chunling; Liang, Qingshuang; Xiao, Xiufeng

Chen, Shunyu; Guo, Rongying; Xie, Chunling; Liang, Qingshuang; Xiao, Xiufeng.

Afiliação

Chen S; Fujian Provincial Key Laboratory of Advanced Materials Oriented Chemical Engineering, College of Chemistry and Material Science, Fujian Normal University, Fuzhou, Fujian 350007, China.
Guo R; Fujian Provincial Key Laboratory of Advanced Materials Oriented Chemical Engineering, College of Chemistry and Material Science, Fujian Normal University, Fuzhou, Fujian 350007, China.
Xie C; Fujian Provincial Key Laboratory of Advanced Materials Oriented Chemical Engineering, College of Chemistry and Material Science, Fujian Normal University, Fuzhou, Fujian 350007, China.
Liang Q; Fujian Provincial Key Laboratory of Advanced Materials Oriented Chemical Engineering, College of Chemistry and Material Science, Fujian Normal University, Fuzhou, Fujian 350007, China.
Xiao X; Fujian Provincial Key Laboratory of Advanced Materials Oriented Chemical Engineering, College of Chemistry and Material Science, Fujian Normal University, Fuzhou, Fujian 350007, China. Electronic address: xfxiao@fjnu.edu.cn.

Mater Sci Eng C Mater Biol Appl ; 110: 110655, 2020 May.

Article em En | MEDLINE | ID: mdl-32204083

Assuntos

Alendronato/administração & dosagem; Aminas/química; Biomimética; Sistemas de Liberação de Medicamentos; Hidroxiapatitas/química; Microesferas; Minerais/química; Nanopartículas/química; Poliésteres/química; Adsorção; Animais; Linhagem Celular; Proliferação de Células; Cristalização; Liberação Controlada de Fármacos; Camundongos; Padrões de Referência; Soluções; Espectroscopia de Infravermelho com Transformada de Fourier; Difração de Raios X

Palavras-chave

Alendronate; Aminated polylactic acid; Biomimetic mineralization; Hydroxyapatite; Nanofibrous microspheres; Sustained release

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Poliésteres / Sistemas de Liberação de Medicamentos / Alendronato / Biomimética / Nanopartículas / Aminas / Hidroxiapatitas / Microesferas / Minerais Limite: Animals Idioma: En Revista: Mater Sci Eng C Mater Biol Appl Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China

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