Urolithin a attenuates IL-1ß-induced inflammatory responses and cartilage degradation via inhibiting the MAPK/NF-&#954;B signaling pathways in rat articular chondrocytes.

Ding, Sheng-Long; Pang, Zhi-Ying; Chen, Xue-Mei; Li, Zheng; Liu, Xin-Xin; Zhai, Qi-Lin; Huang, Jun-Ming; Ruan, Zhi-Yong

Urolithin a attenuates IL-1ß-induced inflammatory responses and cartilage degradation via inhibiting the MAPK/NF-κB signaling pathways in rat articular chondrocytes.

Ding, Sheng-Long; Pang, Zhi-Ying; Chen, Xue-Mei; Li, Zheng; Liu, Xin-Xin; Zhai, Qi-Lin; Huang, Jun-Ming; Ruan, Zhi-Yong.

Afiliação

Ding SL; 1Department of Orthopaedic Surgery, Qingpu Branch of Zhongshan Hospital, Fudan University, 1158 Gong Yuan Dong Road, Qingpu District, Shanghai, 201700 China.
Pang ZY; 2Department of Orthopaedic Surgery, Zhongshan Hospital, Fudan University, 180 Feng Lin Road, Xuhui District, Shanghai, 200032 China.
Chen XM; 3Department of Anesthesiology, Shanghai JiaoTong University Affiliated Shanghai Sixth People's Hospital, Shanghai, 200233 China.
Li Z; 2Department of Orthopaedic Surgery, Zhongshan Hospital, Fudan University, 180 Feng Lin Road, Xuhui District, Shanghai, 200032 China.
Liu XX; 2Department of Orthopaedic Surgery, Zhongshan Hospital, Fudan University, 180 Feng Lin Road, Xuhui District, Shanghai, 200032 China.
Zhai QL; 1Department of Orthopaedic Surgery, Qingpu Branch of Zhongshan Hospital, Fudan University, 1158 Gong Yuan Dong Road, Qingpu District, Shanghai, 201700 China.
Huang JM; 2Department of Orthopaedic Surgery, Zhongshan Hospital, Fudan University, 180 Feng Lin Road, Xuhui District, Shanghai, 200032 China.
Ruan ZY; 1Department of Orthopaedic Surgery, Qingpu Branch of Zhongshan Hospital, Fudan University, 1158 Gong Yuan Dong Road, Qingpu District, Shanghai, 201700 China.

J Inflamm (Lond) ; 17: 13, 2020.

Article em En | MEDLINE | ID: mdl-32210738

Palavras-chave

Inflammation; MAPK; NF-κB; Osteoarthritis; Urolithin a

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Texto completo: 1 Bases de dados: MEDLINE Idioma: En Revista: J Inflamm (Lond) Ano de publicação: 2020 Tipo de documento: Article