Ordered Lipid Domains Assemble via Concerted Recruitment of Constituents from Both Membrane Leaflets.
Phys Rev Lett
; 124(10): 108102, 2020 Mar 13.
Article
em En
| MEDLINE
| ID: mdl-32216409
ABSTRACT
Lipid rafts serve as anchoring platforms for membrane proteins. Thus far they escaped direct observation by light microscopy due to their small size. Here we used differently colored dyes as reporters for the registration of both ordered and disordered lipids from the two leaves of a freestanding bilayer. Photoswitchable lipids dissolved or reformed the domains. Measurements of domain mobility indicated the presence of 120 nm wide ordered and 40 nm wide disordered domains. These sizes are in line with the predicted roles of line tension and membrane undulation as driving forces for alignment.
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Microdomínios da Membrana
/
Lipídeos de Membrana
Tipo de estudo:
Prognostic_studies
Idioma:
En
Revista:
Phys Rev Lett
Ano de publicação:
2020
Tipo de documento:
Article
País de afiliação:
Áustria