Proteomics analysis of tumor exosomes reveals vital pathways of Jinfukang inhibiting circulating tumor cells metastasis in lung cancer.

Que, Zu-Jun; Luo, Bin; Wang, Chen-Tong; Qian, Fang-Fang; Jiang, Yi; Li, Yan; Han, Xiang-Hui; Li, He-Gen; Liu, Jia-Xiang; Tian, Jian-Hui

Que, Zu-Jun; Luo, Bin; Wang, Chen-Tong; Qian, Fang-Fang; Jiang, Yi; Li, Yan; Han, Xiang-Hui; Li, He-Gen; Liu, Jia-Xiang; Tian, Jian-Hui.

Afiliação

Que ZJ; Institute of Traditional Chinese Medicine Oncology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200032, China; School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China. Electronic address: zujunque@shutcm.edu.cn.
Luo B; Institute of Traditional Chinese Medicine Oncology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200032, China. Electronic address: luo2014bin@163.com.
Wang CT; State Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200240, China. Electronic address: 13122310063@163.com.
Qian FF; Department of Oncology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200032, China. Electronic address: 18883873419@163.com.
Jiang Y; Department of Oncology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200032, China. Electronic address: 877708348@qq.com.
Li Y; Department of Oncology, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200071, China. Electronic address: liyan31415@163.com.
Han XH; Institute of Chinese Traditional Surgery, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200032, China. Electronic address: hanxianghui1106@163.com.
Li HG; Department of Oncology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200032, China. Electronic address: shlaogen@163.com.
Liu JX; Department of Oncology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200032, China. Electronic address: tjhhawk@163.com.
Tian JH; Institute of Traditional Chinese Medicine Oncology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200032, China; Department of Oncology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200032, China. Electronic address: hawk7150@hot

J Ethnopharmacol ; 256: 112802, 2020 Jun 28.

Article em En | MEDLINE | ID: mdl-32240782

Assuntos

Medicamentos de Ervas Chinesas/farmacologia; Exossomos/efeitos dos fármacos; Exossomos/metabolismo; Neoplasias Pulmonares/tratamento farmacológico; Neoplasias Pulmonares/metabolismo; Células Neoplásicas Circulantes/efeitos dos fármacos; Células Neoplásicas Circulantes/metabolismo; Apoptose/efeitos dos fármacos; Linhagem Celular Tumoral; Proliferação de Células/efeitos dos fármacos; Regulação Neoplásica da Expressão Gênica/efeitos dos fármacos; Humanos; MicroRNAs/metabolismo; Proteômica/métodos; Transdução de Sinais/efeitos dos fármacos

Palavras-chave

Circulating tumor cells; Exosomes; Lung cancer; Metastasis; Proteome

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Medicamentos de Ervas Chinesas / Exossomos / Neoplasias Pulmonares / Células Neoplásicas Circulantes Limite: Humans Idioma: En Revista: J Ethnopharmacol Ano de publicação: 2020 Tipo de documento: Article

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