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NLRP3 inflammasome as prognostic factor and therapeutic target in primary progressive multiple sclerosis patients.
Malhotra, Sunny; Costa, Carme; Eixarch, Herena; Keller, Christian W; Amman, Lukas; Martínez-Banaclocha, Helios; Midaglia, Luciana; Sarró, Eduard; Machín-Díaz, Isabel; Villar, Luisa M; Triviño, Juan Carlos; Oliver-Martos, Begoña; Parladé, Laura Navarro; Calvo-Barreiro, Laura; Matesanz, Fuencisla; Vandenbroeck, Koen; Urcelay, Elena; Martínez-Ginés, María-Luisa; Tejeda-Velarde, Amalia; Fissolo, Nicolás; Castilló, Joaquín; Sanchez, Alex; Robertson, Avril A B; Clemente, Diego; Prinz, Marco; Pelegrin, Pablo; Lünemann, Jan D; Espejo, Carmen; Montalban, Xavier; Comabella, Manuel.
Afiliação
  • Malhotra S; Servei de Neurologia-Neuroimmunologia, Centre d'Esclerosi Múltiple de Catalunya (Cemcat), Institut de Recerca Vall d'Hebron (VHIR), Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain.
  • Costa C; Servei de Neurologia-Neuroimmunologia, Centre d'Esclerosi Múltiple de Catalunya (Cemcat), Institut de Recerca Vall d'Hebron (VHIR), Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain.
  • Eixarch H; Servei de Neurologia-Neuroimmunologia, Centre d'Esclerosi Múltiple de Catalunya (Cemcat), Institut de Recerca Vall d'Hebron (VHIR), Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain.
  • Keller CW; Department of Neurology with Institute of Translational Neurology, University Hospital Münster, Münster, Germany.
  • Amman L; Institute of Experimental Immunology, Laboratory of Neuroinflammation, University of Zurich, Zurich, Switzerland.
  • Martínez-Banaclocha H; Institute of Neuropathology, Medical Faculty, University of Freiburg, Freiburg, Germany.
  • Midaglia L; Faculty of Biology, University of Freiburg, Freiburg, Germany.
  • Sarró E; Biomedical Research Institute of Murcia (IMIB-Arrixaca), University Clinical Hospital Virgen de la Arrixaca, Murcia, Spain.
  • Machín-Díaz I; Servei de Neurologia-Neuroimmunologia, Centre d'Esclerosi Múltiple de Catalunya (Cemcat), Institut de Recerca Vall d'Hebron (VHIR), Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain.
  • Villar LM; Renal Physiopathology Group, Institut de Recerca Vall d'Hebron (VHIR) - CIBBIM Nanomedicine, Barcelona, Spain.
  • Triviño JC; Grupo de Neuroinmuno-Reparación, Hospital Nacional de Parapléjicos-SESCAM, Toledo, Spain.
  • Oliver-Martos B; Departments of Immunology and Neurology, Multiple Sclerosis Unit, Hospital Ramon y Cajal, (IRYCIS), Madrid, Spain.
  • Parladé LN; Genomic Systems, Valencia, Spain.
  • Calvo-Barreiro L; Neuroimmunology and Neuroinflammation Group, Instituto de Investigación Biomédica de Málaga-IBIMA, UGC Neurociencias, Hospital Regional Universitario de Málaga, Málaga, Spain.
  • Matesanz F; Servei de Neurologia-Neuroimmunologia, Centre d'Esclerosi Múltiple de Catalunya (Cemcat), Institut de Recerca Vall d'Hebron (VHIR), Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain.
  • Vandenbroeck K; Servei de Neurologia-Neuroimmunologia, Centre d'Esclerosi Múltiple de Catalunya (Cemcat), Institut de Recerca Vall d'Hebron (VHIR), Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain.
  • Urcelay E; Department of Cell Biology and Immunology, Instituto de Parasitología y Biomedicina "López Neyra", Consejo Superior de Investigaciones Científicas (IPBLN-CSIC), Granada, Spain.
  • Martínez-Ginés ML; Universidad del País Vasco (UPV/EHU), Leioa, Spain.
  • Tejeda-Velarde A; IKERBASQUE, Basque Foundation for Science, Bilbao, Spain.
  • Fissolo N; Hospital Clínico San Carlos, Instituto de Investigación Sanitaria San Carlos (IdISSC), Madrid, Spain.
  • Castilló J; Department of Neurology, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
  • Sanchez A; Departments of Immunology and Neurology, Multiple Sclerosis Unit, Hospital Ramon y Cajal, (IRYCIS), Madrid, Spain.
  • Robertson AAB; Servei de Neurologia-Neuroimmunologia, Centre d'Esclerosi Múltiple de Catalunya (Cemcat), Institut de Recerca Vall d'Hebron (VHIR), Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain.
  • Clemente D; Servei de Neurologia-Neuroimmunologia, Centre d'Esclerosi Múltiple de Catalunya (Cemcat), Institut de Recerca Vall d'Hebron (VHIR), Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain.
  • Prinz M; Department of Genetics, Microbiology and Statistics, Universitat de Barcelona, Barcelona, Spain.
  • Pelegrin P; Statistics and Bioinformatics Unit, Vall d'Hebron Institut de Recerca, Barcelona, Spain.
  • Lünemann JD; School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Australia.
  • Espejo C; Grupo de Neuroinmuno-Reparación, Hospital Nacional de Parapléjicos-SESCAM, Toledo, Spain.
  • Montalban X; Institute of Neuropathology, Medical Faculty, University of Freiburg, Freiburg, Germany.
  • Comabella M; Signalling Research Centres BIOSS and CIBSS, University of Freiburg, Freiburg, Germany.
Brain ; 143(5): 1414-1430, 2020 05 01.
Article em En | MEDLINE | ID: mdl-32282893
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Esclerose Múltipla Crônica Progressiva / Interleucina-1beta / Inflamassomos / Proteína 3 que Contém Domínio de Pirina da Família NLR Tipo de estudo: Prognostic_studies Limite: Adult / Animals / Female / Humans / Male Idioma: En Revista: Brain Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Espanha
Texto completo
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Esclerose Múltipla Crônica Progressiva / Interleucina-1beta / Inflamassomos / Proteína 3 que Contém Domínio de Pirina da Família NLR Tipo de estudo: Prognostic_studies Limite: Adult / Animals / Female / Humans / Male Idioma: En Revista: Brain Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Espanha