A medicinal chemistry perspective of drug repositioning: Recent advances and challenges in drug discovery.

Pillaiyar, Thanigaimalai; Meenakshisundaram, Sangeetha; Manickam, Manoj; Sankaranarayanan, Murugesan

Pillaiyar, Thanigaimalai; Meenakshisundaram, Sangeetha; Manickam, Manoj; Sankaranarayanan, Murugesan.

Afiliação

Pillaiyar T; PharmaCenter Bonn, Pharmaceutical Institute, Department of Pharmaceutical & Medicinal Chemistry, University of Bonn, An der Immenburg 4, D-53121, Bonn, Germany. Electronic address: thanigai@uni-bonn.de.
Meenakshisundaram S; Department of Chemistry, Sri Krishna College of Engineering and Technology, Coimbatore, Tamil Nadu, India.
Manickam M; Department of Chemistry, PSG Institute of Technology and Applied Research, Coimbatore, Tamil Nadu, India.
Sankaranarayanan M; Department of Pharmacy, Birla Institute of Technology and Science Pilani, Pilani Campus, Pilani, 333031, Rajasthan, India.

Eur J Med Chem ; 195: 112275, 2020 Jun 01.

Article em En | MEDLINE | ID: mdl-32283298

Assuntos

Descoberta de Drogas/métodos; Reposicionamento de Medicamentos/métodos; Animais; Química Farmacêutica; Humanos

Palavras-chave

Cancer; Drug discovery; Drug repositioning; Drug reprofiling; Inflammation; Neurodegenerative diseases; Recycling of drugs; Skin diseases

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Descoberta de Drogas / Reposicionamento de Medicamentos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Eur J Med Chem Ano de publicação: 2020 Tipo de documento: Article

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