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Conditional deletion of Nedd4-2 in lung epithelial cells causes progressive pulmonary fibrosis in adult mice.
Duerr, Julia; Leitz, Dominik H W; Szczygiel, Magdalena; Dvornikov, Dmytro; Fraumann, Simon G; Kreutz, Clemens; Zadora, Piotr K; Seyhan Agircan, Ayça; Konietzke, Philip; Engelmann, Theresa A; Hegermann, Jan; Mulugeta, Surafel; Kawabe, Hiroshi; Knudsen, Lars; Ochs, Matthias; Rotin, Daniela; Muley, Thomas; Kreuter, Michael; Herth, Felix J F; Wielpütz, Mark O; Beers, Michael F; Klingmüller, Ursula; Mall, Marcus A.
Afiliação
  • Duerr J; Department of Translational Pulmonology, University of Heidelberg, Im Neuenheimer Feld 156, 69120, Heidelberg, Germany. julia.duerr@charite.de.
  • Leitz DHW; Translational Lung Research Center (TLRC), German Center for Lung Research (DZL), Im Neuenheimer Feld 156, 69120, Heidelberg, Germany. julia.duerr@charite.de.
  • Szczygiel M; Department of Pediatric Pulmonology, Immunology and Critical Care Medicine, Charité-Universitätsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Germany. julia.duerr@charite.de.
  • Dvornikov D; Department of Translational Pulmonology, University of Heidelberg, Im Neuenheimer Feld 156, 69120, Heidelberg, Germany.
  • Fraumann SG; Translational Lung Research Center (TLRC), German Center for Lung Research (DZL), Im Neuenheimer Feld 156, 69120, Heidelberg, Germany.
  • Kreutz C; Department of Pediatric Pulmonology, Immunology and Critical Care Medicine, Charité-Universitätsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Germany.
  • Zadora PK; Translational Lung Research Center (TLRC), German Center for Lung Research (DZL), Im Neuenheimer Feld 156, 69120, Heidelberg, Germany.
  • Seyhan Agircan A; Division of Systems Biology of Signal Transduction, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.
  • Konietzke P; Faculty of Biosciences, University of Heidelberg, Im Neuenheimer Feld 234, 69120, Heidelberg, Germany.
  • Engelmann TA; Translational Lung Research Center (TLRC), German Center for Lung Research (DZL), Im Neuenheimer Feld 156, 69120, Heidelberg, Germany.
  • Hegermann J; Division of Systems Biology of Signal Transduction, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.
  • Mulugeta S; Faculty of Biosciences, University of Heidelberg, Im Neuenheimer Feld 234, 69120, Heidelberg, Germany.
  • Kawabe H; Department of Translational Pulmonology, University of Heidelberg, Im Neuenheimer Feld 156, 69120, Heidelberg, Germany.
  • Knudsen L; Translational Lung Research Center (TLRC), German Center for Lung Research (DZL), Im Neuenheimer Feld 156, 69120, Heidelberg, Germany.
  • Ochs M; Institute of Medical Biometry and Statistics, University of Freiburg, Stefan-Meier-Straße 26, 79104, Freiburg, Germany.
  • Rotin D; Centre for Integrative Biological Signaling Studies (CIBSS), University of Freiburg, Schänzlestr. 18, 79104, Freiburg, Germany.
  • Muley T; Translational Lung Research Center (TLRC), German Center for Lung Research (DZL), Im Neuenheimer Feld 156, 69120, Heidelberg, Germany.
  • Kreuter M; Division of Systems Biology of Signal Transduction, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.
  • Herth FJF; Faculty of Biosciences, University of Heidelberg, Im Neuenheimer Feld 234, 69120, Heidelberg, Germany.
  • Wielpütz MO; Department of Translational Pulmonology, University of Heidelberg, Im Neuenheimer Feld 156, 69120, Heidelberg, Germany.
  • Beers MF; Translational Lung Research Center (TLRC), German Center for Lung Research (DZL), Im Neuenheimer Feld 156, 69120, Heidelberg, Germany.
  • Klingmüller U; Translational Lung Research Center (TLRC), German Center for Lung Research (DZL), Im Neuenheimer Feld 156, 69120, Heidelberg, Germany.
  • Mall MA; Department of Diagnostic and Interventional Radiology, University of Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg, Germany.
Nat Commun ; 11(1): 2012, 2020 04 24.
Article em En | MEDLINE | ID: mdl-32332792
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Células Epiteliais / Fibrose Pulmonar Idiopática / Ubiquitina-Proteína Ligases Nedd4 / Pulmão Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Adult / Aged / Animals / Humans / Middle aged Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Células Epiteliais / Fibrose Pulmonar Idiopática / Ubiquitina-Proteína Ligases Nedd4 / Pulmão Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Adult / Aged / Animals / Humans / Middle aged Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Alemanha