Molecular imaging reveals biodistribution of P-cadherin LP-DART bispecific and trafficking of adoptively transferred T cells in mouse xenograft model.

Gupta, Vijay R; Root, Adam; Fisher, Timothy; Norberg, Rand; David, John; Clark, Tracey; Cohen, Justin; May, Chad; Giddabasappa, Anand

Gupta, Vijay R; Root, Adam; Fisher, Timothy; Norberg, Rand; David, John; Clark, Tracey; Cohen, Justin; May, Chad; Giddabasappa, Anand.

Afiliação

Gupta VR; Global Science & Technology (GST) - Comparative Medicine, Pfizer Global Research Development and Medical, San Diego, CA 92121, USA.
Root A; BioMedicine Design, Cambridge, MA 02139, USA.
Fisher T; Oncology Research and Development, San Diego, CA 92121, USA.
Norberg R; Global Science & Technology (GST) - Comparative Medicine, Pfizer Global Research Development and Medical, San Diego, CA 92121, USA.
David J; Global Science & Technology (GST) - Comparative Medicine, Pfizer Global Research Development and Medical, San Diego, CA 92121, USA.
Clark T; PDM Biotherapeutics, Pfizer Inc., San Diego, CA 92121, USA.
Cohen J; BioMedicine Design, Cambridge, MA 02139, USA.
May C; Oncology Research and Development, San Diego, CA 92121, USA.
Giddabasappa A; Global Science & Technology (GST) - Comparative Medicine, Pfizer Global Research Development and Medical, San Diego, CA 92121, USA.

Oncotarget ; 11(15): 1344-1357, 2020 Apr 14.

Article em En | MEDLINE | ID: mdl-32341754

Palavras-chave

T cells; biodistribution; bispecific antibody; molecular imaging; tumor targeting

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Texto completo: 1 Bases de dados: MEDLINE Idioma: En Revista: Oncotarget Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos