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Parsaclisib Is a Next-Generation Phosphoinositide 3-Kinase δ Inhibitor with Reduced Hepatotoxicity and Potent Antitumor and Immunomodulatory Activities in Models of B-Cell Malignancy.
Shin, Niu; Stubbs, Matthew; Koblish, Holly; Yue, Eddy W; Soloviev, Maxim; Douty, Brent; Wang, Kathy He; Wang, Qian; Gao, Mingming; Feldman, Patricia; Yang, Gengjie; Hall, Leslie; Hansbury, Michael; O'Connor, Sybil; Leffet, Lynn; Collins, Robert; Katiyar, Kamna; He, Xin; Waeltz, Paul; Collier, Paul; Lu, Jin; Li, Yun-Long; Li, Yanlong; Liu, Phillip C C; Burn, Timothy; Covington, Maryanne; Diamond, Sharon; Shuey, Dana; Roberts, Alan; Yeleswaram, Swamy; Hollis, Greg; Metcalf, Brian; Yao, Wenqing; Huber, Reid; Combs, Andrew; Newton, Robert; Scherle, Peggy.
Afiliação
  • Shin N; Incyte Research Institute, Wilmington, Delaware nshin@incyte.com.
  • Stubbs M; Incyte Research Institute, Wilmington, Delaware.
  • Koblish H; Incyte Research Institute, Wilmington, Delaware.
  • Yue EW; Incyte Research Institute, Wilmington, Delaware.
  • Soloviev M; Incyte Research Institute, Wilmington, Delaware.
  • Douty B; Incyte Research Institute, Wilmington, Delaware.
  • Wang KH; Incyte Research Institute, Wilmington, Delaware.
  • Wang Q; Incyte Research Institute, Wilmington, Delaware.
  • Gao M; Incyte Research Institute, Wilmington, Delaware.
  • Feldman P; Incyte Research Institute, Wilmington, Delaware.
  • Yang G; Incyte Research Institute, Wilmington, Delaware.
  • Hall L; Incyte Research Institute, Wilmington, Delaware.
  • Hansbury M; Incyte Research Institute, Wilmington, Delaware.
  • O'Connor S; Incyte Research Institute, Wilmington, Delaware.
  • Leffet L; Incyte Research Institute, Wilmington, Delaware.
  • Collins R; Incyte Research Institute, Wilmington, Delaware.
  • Katiyar K; Incyte Research Institute, Wilmington, Delaware.
  • He X; Incyte Research Institute, Wilmington, Delaware.
  • Waeltz P; Incyte Research Institute, Wilmington, Delaware.
  • Collier P; Incyte Research Institute, Wilmington, Delaware.
  • Lu J; Incyte Research Institute, Wilmington, Delaware.
  • Li YL; Incyte Research Institute, Wilmington, Delaware.
  • Li Y; Incyte Research Institute, Wilmington, Delaware.
  • Liu PCC; Incyte Research Institute, Wilmington, Delaware.
  • Burn T; Incyte Research Institute, Wilmington, Delaware.
  • Covington M; Incyte Research Institute, Wilmington, Delaware.
  • Diamond S; Incyte Research Institute, Wilmington, Delaware.
  • Shuey D; Incyte Research Institute, Wilmington, Delaware.
  • Roberts A; Incyte Research Institute, Wilmington, Delaware.
  • Yeleswaram S; Incyte Research Institute, Wilmington, Delaware.
  • Hollis G; Incyte Research Institute, Wilmington, Delaware.
  • Metcalf B; Incyte Research Institute, Wilmington, Delaware.
  • Yao W; Incyte Research Institute, Wilmington, Delaware.
  • Huber R; Incyte Research Institute, Wilmington, Delaware.
  • Combs A; Incyte Research Institute, Wilmington, Delaware.
  • Newton R; Incyte Research Institute, Wilmington, Delaware.
  • Scherle P; Incyte Research Institute, Wilmington, Delaware.
J Pharmacol Exp Ther ; 374(1): 211-222, 2020 07.
Article em En | MEDLINE | ID: mdl-32345620
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Pirazóis / Pirimidinas / Pirrolidinas / Fosfatidilinositol 3-Quinases / Inibidores de Fosfoinositídeo-3 Quinase / Fígado / Linfoma Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: J Pharmacol Exp Ther Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Pirazóis / Pirimidinas / Pirrolidinas / Fosfatidilinositol 3-Quinases / Inibidores de Fosfoinositídeo-3 Quinase / Fígado / Linfoma Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: J Pharmacol Exp Ther Ano de publicação: 2020 Tipo de documento: Article