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Halting the vicious cycle within the multiple myeloma ecosystem: blocking JAM-A on bone marrow endothelial cells restores angiogenic homeostasis and suppresses tumor progression.
Solimando, Antonio G; Da Vià, Matteo C; Leone, Patrizia; Borrelli, Paola; Croci, Giorgio A; Tabares, Paula; Brandl, Andreas; Di Lernia, Giuseppe; Bianchi, Francesco P; Tafuri, Silvio; Steinbrunn, Torsten; Balduini, Alessandra; Melaccio, Assunta; De Summa, Simona; Argentiero, Antonella; Rauert-Wunderlich, Hilka; Frassanito, Maria A; Ditonno, Paolo; Henke, Erik; Klapper, Wolfram; Ria, Roberto; Terragna, Carolina; Rasche, Leo; Rosenwald, Andreas; Kortüm, Martin K; Cavo, Michele; Ribatti, Domenico; Racanelli, Vito; Einsele, Hermann; Vacca, Angelo; Beilhack, Andreas.
Afiliação
  • Solimando AG; Department of Medicine II, University Hospital of Würzburg, Würzburg, Germany; 2IRCCS Istituto Tumori Giovanni Paolo II of Bari, Italy; 3University of Bari Aldo Moro Medical School, Bari, Italy.
  • Da Vià MC; Department of Medicine II, University Hospital of Würzburg, Würzburg, Germany.
  • Leone P; University of Bari Aldo Moro Medical School, Bari, Italy.
  • Borrelli P; Department of Public Health, Experimental and Forensic Medicine, University of Pavia, Pavia, Italy.
  • Croci GA; Department of Pathology, University of Kiel/University Hospital Schleswig-Holstein, Kiel, Germany; Department of Pathophysiology and Transplantation, University of Milan and Fondazione IRCCS, Ca' Granda, Milan, Italy.
  • Tabares P; Department of Medicine II, University Hospital of Würzburg, Würzburg, Germany; 7Interdisciplinary Center for Clinical Research Laboratory, University Hospital of Würzburg, Würzburg, Germany.
  • Brandl A; Department of Medicine II, University Hospital of Würzburg, Würzburg, Germany; 7Interdisciplinary Center for Clinical Research Laboratory, University Hospital of Würzburg, Würzburg, Germany.
  • Di Lernia G; University of Bari Aldo Moro Medical School, Bari, Italy.
  • Bianchi FP; Department of Biomedical Science and Human Oncology, University of Aldo Moro Medical School, Bari, Italy.
  • Tafuri S; Department of Biomedical Science and Human Oncology, University of Aldo Moro Medical School, Bari, Italy.
  • Steinbrunn T; Department of Medicine II, University Hospital of Würzburg, Würzburg, Germany.
  • Balduini A; Department of Molecular Medicine, University of Pavia, Pavia, Italy 10Department of Biomedical Engineering, Tufts University, Medford, MA, USA.
  • Melaccio A; University of Bari Aldo Moro Medical School, Bari, Italy.
  • De Summa S; Molecular Diagnostics and Pharmacogenetics Unit, IRCCS Istituto Tumori Giovanni Paolo II, Bari, Italy.
  • Argentiero A; IRCCS Istituto Tumori.
  • Rauert-Wunderlich H; Institute of Pathology, University of Würzburg, Würzburg, Germany.
  • Frassanito MA; University of Bari Aldo Moro Medical School, Bari, Italy.
  • Ditonno P; IRCCS Istituto Tumori.
  • Henke E; Institute of Anatomy and Cell Biology, Julius-Maximilians Universität Würzburg, Würzburg, Germany.
  • Klapper W; Department of Pathology, University of Kiel/University Hospital Schleswig-Holstein, Kiel, Germany.
  • Ria R; University of Bari Aldo Moro Medical School, Bari, Italy.
  • Terragna C; Institute of Hematology L. and A. Seràgnoli, Bologna, Italy.
  • Rasche L; Department of Medicine II, University Hospital of Würzburg, Würzburg, Germany.
  • Rosenwald A; Institute of Pathology, University of Würzburg, Würzburg, Germany.
  • Kortüm MK; Department of Medicine II, University Hospital of Würzburg, Würzburg, Germany.
  • Cavo M; Institute of Hematology L. and A. Seràgnoli, Bologna, Italy.
  • Ribatti D; Department of Basic Medical Sciences, Neurosciences and Sensory Organs, University of Bari Aldo Moro Medical School, Bari, Italy.
  • Racanelli V; University of Bari Aldo Moro Medical School, Bari, Italy.
  • Einsele H; Department of Medicine II, University Hospital of Würzburg, Würzburg, Germany.
  • Vacca A; University of Bari Aldo Moro Medical School, Bari, Italy.
  • Beilhack A; Department of Medicine II, University Hospital of Würzburg, Würzburg, Germany; 7Interdisciplinary Center for Clinical Research Laboratory, University Hospital of Würzburg, Würzburg, Germany.
Haematologica ; 106(7): 1943-1956, 2021 07 01.
Article em En | MEDLINE | ID: mdl-32354870
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Molécula A de Adesão Juncional / Mieloma Múltiplo Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Haematologica Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Itália
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Molécula A de Adesão Juncional / Mieloma Múltiplo Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Haematologica Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Itália