[Pathology of the nipple-areola complex : I. Paget's disease of the nipple, variants, and differential diagnoses]. / Pathologie der Mamillenregion : I. Morbus Paget der Mamille, Varianten und Differenzialdiagnosen.
Pathologe
; 41(4): 393-399, 2020 Jul.
Article
em De
| MEDLINE
| ID: mdl-32405655
ABSTRACT
The classical Paget's disease of the nipple is histologically characterized by tumor cell infiltration originating in intraductal or invasive breast carcinoma, immunohistologically by a frequent overexpression of HER2 and clinically by eczema-like changes of the nipple and areola. Variants with different histological, immunohistological, and clinical features are observed in nonclassical forms of Paget's disease, such as isolated Paget's disease of the nipple, anaplastic Paget's disease, Paget's disease with invasion, and pigmented Paget's disease of the nipple. In the differential diagnosis of Paget's disease, benign changes have to be considered, including Toker cell hyperplasia, nipple eczema, and rare dermatoses.
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Texto completo:
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Bases de dados:
MEDLINE
Assunto principal:
Neoplasias da Mama
/
Doença de Paget Mamária
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
Idioma:
De
Revista:
Pathologe
Ano de publicação:
2020
Tipo de documento:
Article