Genotoxicity of aldehyde mixtures: profile of exocyclic DNA-adducts as a biomarker of exposure to tobacco smoke.

Alamil, Héléna; Galanti, Laurence; Heutte, Natacha; Van Der Schueren, Marie; Dagher, Zeina; Lechevrel, Mathilde

Alamil, Héléna; Galanti, Laurence; Heutte, Natacha; Van Der Schueren, Marie; Dagher, Zeina; Lechevrel, Mathilde.

Afiliação

Alamil H; Normandie University, UNICAEN, ABTE EA4651, Caen, France; CCC François Baclesse, UNICANCER, Caen, France; L2GE, Microbiology-Tox/Ecotox Team, Faculty of Sciences, Lebanese University, Fanar, Lebanon. Electronic address: helena.alamil@unicaen.fr.
Galanti L; Tabacology Unit, CHU UCL Namur Asbl, Belgium.
Heutte N; CCC François Baclesse, UNICANCER, Caen, France; Normandie University, UNIROUEN, CETAPS EA3832, Mont Saint Aignan, Cedex, France.
Van Der Schueren M; Tabacology Unit, Department of Addictology, CHU Caen Normandie, France.
Dagher Z; L2GE, Microbiology-Tox/Ecotox Team, Faculty of Sciences, Lebanese University, Fanar, Lebanon.
Lechevrel M; Normandie University, UNICAEN, ABTE EA4651, Caen, France; CCC François Baclesse, UNICANCER, Caen, France. Electronic address: mathilde.lechevrel@unicaen.fr.

Toxicol Lett ; 331: 57-64, 2020 Oct 01.

Article em En | MEDLINE | ID: mdl-32442718

Assuntos

Aldeídos/toxicidade; Adutos de DNA/sangue; DNA/efeitos dos fármacos; Mutagênicos/toxicidade; Nicotiana; Fumar/sangue; DNA/genética; Relação Dose-Resposta a Droga; Humanos; Nicotiana/química

Palavras-chave

Adducts; Aldehydes; Biomarkers; Oxidative stress; Tobacco smoke; UHPLC-ESI-MS/MS

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Nicotiana / DNA / Fumar / Adutos de DNA / Aldeídos / Mutagênicos Limite: Humans Idioma: En Revista: Toxicol Lett Ano de publicação: 2020 Tipo de documento: Article

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google