Full-field optical coherence tomography: novel imaging technique for extemporaneous high-resolution analysis of mucosal architecture in human gut biopsies.
Gut
; 70(1): 6-8, 2021 01.
Article
em En
| MEDLINE
| ID: mdl-32447309
ABSTRACT
Full-field optical coherence tomography (FFOCT) is an imaging technique of biological tissue based on tissue light reflectance analysis. We evaluated the feasibility of imaging fresh digestive mucosal biopsies after a quick mounting procedure (5 min) using two distinct modalities of FFOCT. In static FFOCT mode, we gained high-resolution images of general gut tissue-specific architecture, such as oesophageal papillae, gastric pits, duodenal villi and colonic crypts. In dynamic FFOCT mode, we imaged individual epithelial cells of the mucosal lining with a cellular or subcellular resolution and identified cellular components of the lamina propria. FFOCT represents a promising dye-free imaging tool for on-site analysis of gut tissue remodelling.
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Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Trato Gastrointestinal
/
Tomografia de Coerência Óptica
Limite:
Humans
Idioma:
En
Revista:
Gut
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
França