Your browser doesn't support javascript.
loading
Prolonged tau clearance and stress vulnerability rescue by pharmacological activation of autophagy in tauopathy neurons.
Silva, M Catarina; Nandi, Ghata A; Tentarelli, Sharon; Gurrell, Ian K; Jamier, Tanguy; Lucente, Diane; Dickerson, Bradford C; Brown, Dean G; Brandon, Nicholas J; Haggarty, Stephen J.
Afiliação
  • Silva MC; Chemical Neurobiology Laboratory, Center for Genomic Medicine, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, 185 Cambridge St CPZN 5400, Boston, MA, 02114, USA.
  • Nandi GA; Chemical Neurobiology Laboratory, Center for Genomic Medicine, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, 185 Cambridge St CPZN 5400, Boston, MA, 02114, USA.
  • Tentarelli S; Chemistry, Oncology R&D, AstraZeneca, 35 Gatehouse Dr, Waltham, MA, 02451, USA.
  • Gurrell IK; Neuroscience, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK.
  • Jamier T; Neuroscience, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK.
  • Lucente D; Molecular Neurogenetics Unit, Center for Genomic Medicine, Massachusetts General Hospital and Harvard Medical School, 185 Cambridge St CPZN, RM 5820, Boston, MA, 02114, USA.
  • Dickerson BC; MGH Frontotemporal Disorders Unit, Gerontology Research Unit, Alzheimer's Disease Research Center, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, 149 13th St. Suite 2691, Charlestown, MA, 02129, USA.
  • Brown DG; Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Waltham, MA, USA.
  • Brandon NJ; Neuroscience, BioPharmaceuticals R&D, AstraZeneca, Waltham, MA, USA.
  • Haggarty SJ; Chemical Neurobiology Laboratory, Center for Genomic Medicine, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, 185 Cambridge St CPZN 5400, Boston, MA, 02114, USA. shaggarty@mgh.harvard.edu.
Nat Commun ; 11(1): 3258, 2020 06 26.
Article em En | MEDLINE | ID: mdl-32591533
Assuntos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Autofagia / Estresse Fisiológico / Proteínas tau / Tauopatias / Inibidores de Proteínas Quinases / Neurônios Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Autofagia / Estresse Fisiológico / Proteínas tau / Tauopatias / Inibidores de Proteínas Quinases / Neurônios Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos