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Itaconate is an effector of a Rab GTPase cell-autonomous host defense pathway against Salmonella.
Chen, Meixin; Sun, Hui; Boot, Maikel; Shao, Lin; Chang, Shu-Jung; Wang, Weiwei; Lam, Tukiet T; Lara-Tejero, Maria; Rego, E Hesper; Galán, Jorge E.
Afiliação
  • Chen M; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06536, USA.
  • Sun H; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06536, USA.
  • Boot M; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06536, USA.
  • Shao L; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06536, USA.
  • Chang SJ; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06536, USA.
  • Wang W; WM Keck Foundation Biotechnology Resource Laboratory, Yale University School of Medicine, New Haven, CT 06536, USA.
  • Lam TT; WM Keck Foundation Biotechnology Resource Laboratory, Yale University School of Medicine, New Haven, CT 06536, USA.
  • Lara-Tejero M; Department of Molecular Biophysics and Biochemistry, Yale University School of Medicine, New Haven, CT 06536, USA.
  • Rego EH; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06536, USA.
  • Galán JE; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06536, USA.
Science ; 369(6502): 450-455, 2020 07 24.
Article em En | MEDLINE | ID: mdl-32703879

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Infecções por Salmonella / Salmonella typhimurium / Salmonella enterica / Proteínas rab de Ligação ao GTP / Hidroliases Limite: Animals / Humans Idioma: En Revista: Science Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Infecções por Salmonella / Salmonella typhimurium / Salmonella enterica / Proteínas rab de Ligação ao GTP / Hidroliases Limite: Animals / Humans Idioma: En Revista: Science Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos