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A First Case of Acute Cerebellitis Associated with Coronavirus Disease (COVID-19): a Case Report and Literature Review.
Fadakar, Nima; Ghaemmaghami, Sara; Masoompour, Seyed Masoom; Shirazi Yeganeh, Babak; Akbari, Ali; Hooshmandi, Sedighe; Ostovan, Vahid Reza.
Afiliação
  • Fadakar N; Clinical Neurology Research Center, Shiraz University of Medical Sciences, Shiraz, 7193635899, Iran.
  • Ghaemmaghami S; Clinical Neurology Research Center, Shiraz University of Medical Sciences, Shiraz, 7193635899, Iran.
  • Masoompour SM; Non-Communicable Diseases Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
  • Shirazi Yeganeh B; Pathology Department, Shiraz University of Medical Sciences, Shiraz, Iran.
  • Akbari A; Anesthesiology Department, Shiraz University of Medical Sciences, Shiraz, Iran.
  • Hooshmandi S; Medical Imaging Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
  • Ostovan VR; Clinical Neurology Research Center, Shiraz University of Medical Sciences, Shiraz, 7193635899, Iran. ostovanv@gmail.com.
Cerebellum ; 19(6): 911-914, 2020 Dec.
Article em En | MEDLINE | ID: mdl-32737799
Novel coronavirus (severe acute respiratory syndrome-coronavirus-2: SARS-CoV-2), which originated from Wuhan, China, has spread to the other countries in a short period of time. We report a 47-year-old male who was admitted to our hospital due to suffering from progressive vertigo and ataxia for 7 days prior to the admission. Neurological examination revealed cerebellar dysfunction, and brain magnetic resonance imaging (MRI) depicted edema of the cerebellar hemisphere associated with leptomeningeal enhancement. Cerebrospinal fluid (CSF) analysis showed mild lymphocytic pleocytosis, elevated protein, and lactate dehydrogenase. SARS-CoV-2 RNA was detected in the oropharyngeal/nasopharyngeal and CSF specimens. As a result, treatment with lopinavir/ritonavir was initiated, and patient symptoms and signs improved significantly during the course of hospitalization. To the best of our knowledge, this is the first case of acute cerebellitis associated with COVID-19 disease which is reported in the literature so far.
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Pneumonia Viral / Doenças Cerebelares / Infecções por Coronavirus / Betacoronavirus Tipo de estudo: Risk_factors_studies Limite: Humans / Male / Middle aged Idioma: En Revista: Cerebellum Assunto da revista: CEREBRO Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Irã

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Pneumonia Viral / Doenças Cerebelares / Infecções por Coronavirus / Betacoronavirus Tipo de estudo: Risk_factors_studies Limite: Humans / Male / Middle aged Idioma: En Revista: Cerebellum Assunto da revista: CEREBRO Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Irã