Value of contrast-enhanced ultrasound in the diagnosis of breast US-BI-RADS 3 and 4 lesions with calcifications.
Clin Radiol
; 75(12): 934-941, 2020 12.
Article
em En
| MEDLINE
| ID: mdl-32814625
ABSTRACT
AIM:
To evaluate the diagnostic performance of contrast-enhanced ultrasound (CEUS) for Breast Imaging-Reporting and Data System for Ultrasound (US-BI-RADS) 3 and 4 lesions with calcifications. MATERIALS ANDMETHODS:
A retrospective study of 168 breast lesions with calcifications detected on both mammography and conventional ultrasonography (US) in 152 patients were categorised as US-BI-RADS 3-4 at US between June 2009 and June 2018. CEUS scores were obtained based on a CEUS five-point scoring system. The combination of US-BI-RADS and CEUS scores created the Rerated BI-RADS (referred to as CEUS-BI-RADS). All results were compared with the histological findings. The diagnostic performances of US and CEUS-BI-RADS were compared.RESULTS:
The diagnostic sensitivity, specificity, and accuracy of US were 81.8% (95% confidence interval [CI] 71.6%, 92%), 85% (95% CI 78.4%, 91.5%), and 83.9% (95% CI 78.4%, 89.5%), respectively, while those for CEUS-BI-RADS were 98.2% (95% CI 94.7%, 100%), 90.3% (95% CI 84.8%, 95.7%), and 92.9% (95% CI 89%, 96.8%), respectively. The diagnostic sensitivity and accuracy values of CEUS-BI-RADS greatly improved compared with those of US (p=0.003 and p=0.004, respectively). The areas under the receiver operating characteristic (ROC) curves for US and CEUS-BI-RADS were 0.888 (95% CI 0.840, 0.936) and 0.963 (95% CI 0.936, 0.989), respectively. The diagnostic efficacy of CEUS-BI-RADS was significantly higher than that of US alone (p=0.004).CONCLUSION:
CEUS-BI-RADS significantly improves the diagnostic accuracy for breast US-BI-RADS 3 and 4 lesions with calcifications compared with US.
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Neoplasias da Mama
/
Calcinose
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Ultrassonografia Mamária
Tipo de estudo:
Diagnostic_studies
/
Observational_studies
Limite:
Adolescent
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Adult
/
Aged
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Female
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Humans
/
Middle aged
Idioma:
En
Revista:
Clin Radiol
Ano de publicação:
2020
Tipo de documento:
Article
País de afiliação:
China