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Sphingosine prevents binding of SARS-CoV-2 spike to its cellular receptor ACE2.
Edwards, Michael J; Becker, Katrin Anne; Gripp, Barbara; Hoffmann, Markus; Keitsch, Simone; Wilker, Barbara; Soddemann, Matthias; Gulbins, Anne; Carpinteiro, Elisa; Patel, Sameer H; Wilson, Gregory C; Pöhlmann, Stefan; Walter, Silke; Fassbender, Klaus; Ahmad, Syed A; Carpinteiro, Alexander; Gulbins, Erich.
Afiliação
  • Edwards MJ; Department of Surgery, University of Cincinnati Medical School, Cincinnati, Ohio, USA.
  • Becker KA; Institute of Molecular Biology, University of Duisburg-Essen, Essen, Germany.
  • Gripp B; Zentrum für Seelische Gesundheit des Kindes- und Jugendalters, Sana-Klinikum Remscheid GmbH, Remscheid, Germany.
  • Hoffmann M; Infection Biology Unit, German Primate Center, Leibniz Institute for Primate Research, Göttingen, Germany; Faculty of Biology and Psychology, University of Göttingen, Göttingen, Germany.
  • Keitsch S; Institute of Molecular Biology, University of Duisburg-Essen, Essen, Germany.
  • Wilker B; Institute of Molecular Biology, University of Duisburg-Essen, Essen, Germany.
  • Soddemann M; Institute of Molecular Biology, University of Duisburg-Essen, Essen, Germany.
  • Gulbins A; Institute of Molecular Biology, University of Duisburg-Essen, Essen, Germany.
  • Carpinteiro E; Institute of Molecular Biology, University of Duisburg-Essen, Essen, Germany.
  • Patel SH; Department of Surgery, University of Cincinnati Medical School, Cincinnati, Ohio, USA.
  • Wilson GC; Department of Surgery, University of Cincinnati Medical School, Cincinnati, Ohio, USA.
  • Pöhlmann S; Infection Biology Unit, German Primate Center, Leibniz Institute for Primate Research, Göttingen, Germany; Faculty of Biology and Psychology, University of Göttingen, Göttingen, Germany.
  • Walter S; Department of Neurology, University Hospital of the Saarland, Homburg/Saar, Germany.
  • Fassbender K; Department of Neurology, University Hospital of the Saarland, Homburg/Saar, Germany.
  • Ahmad SA; Department of Surgery, University of Cincinnati Medical School, Cincinnati, Ohio, USA.
  • Carpinteiro A; Institute of Molecular Biology, University of Duisburg-Essen, Essen, Germany; Department of Hematology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
  • Gulbins E; Department of Surgery, University of Cincinnati Medical School, Cincinnati, Ohio, USA; Institute of Molecular Biology, University of Duisburg-Essen, Essen, Germany. Electronic address: erich.gulbins@uni-due.de.
J Biol Chem ; 295(45): 15174-15182, 2020 11 06.
Article em En | MEDLINE | ID: mdl-32917722
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Esfingosina / Glicoproteína da Espícula de Coronavírus / Enzima de Conversão de Angiotensina 2 Limite: Animals / Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Adicionar na Minha BVS
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XML
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Esfingosina / Glicoproteína da Espícula de Coronavírus / Enzima de Conversão de Angiotensina 2 Limite: Animals / Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos