Comparison of uterine artery Doppler measurements at 6 weeks of pregnancy after IVF between pregnancies that resulted in miscarriage and ongoing pregnancies.
Int J Gynaecol Obstet
; 152(2): 249-255, 2021 Feb.
Article
em En
| MEDLINE
| ID: mdl-32920837
ABSTRACT
OBJECTIVE:
To compare uterine artery pulsatility index (UTPI) at 6 weeks of pregnancy following in vitro fertilization (IVF) and embryo transfer (ET) between clinical pregnancies that resulted in a miscarriage and those that were ongoing beyond 12 weeks.METHODS:
A prospective observational study was conducted in an IVF unit at Prince of Wales Hospital, Hong Kong, between December 1, 2017 and December 31, 2019. UTPI was measured at 6 weeks of pregnancy among women who conceived following IVF/ET.RESULTS:
Among 153 participants, 22 (14.4%) had a miscarriage whereas 131 (85.6%) had an ongoing pregnancy beyond 12 weeks. Median UTPI in pregnancies that ended in a miscarriage was significantly lower than those that progressed beyond 12 weeks (2.1, IQR 1.9-2.4 vs 2.50, IQR 2.2-2.9, respectively; P<0.001). The likelihood of the pregnancy ending in a miscarriage when the UTPI was above the 75th percentile (>2.9), between the 25th-75th percentiles (2.2-2.9), and below the 25th percentile (<2.2) was 0%, 13.2%, and 27.7%, respectively (P=0.001).CONCLUSIONS:
IVF pregnancies that resulted in a miscarriage were associated with reduced resistance to uterine artery blood flow at 6 weeks of pregnancy.Palavras-chave
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Fertilização in vitro
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Aborto Espontâneo
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Transferência Embrionária
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Artéria Uterina
Tipo de estudo:
Observational_studies
Limite:
Adult
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Female
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Humans
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Pregnancy
País/Região como assunto:
Asia
Idioma:
En
Revista:
Int J Gynaecol Obstet
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
China