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Aldh inhibitor restores auditory function in a mouse model of human deafness.
Zhu, Guang-Jie; Gong, Sihao; Ma, Deng-Bin; Tao, Tao; He, Wei-Qi; Zhang, Linqing; Wang, Fang; Qian, Xiao-Yun; Zhou, Han; Fan, Chi; Wang, Pei; Chen, Xin; Zhao, Wei; Sun, Jie; Chen, Huaqun; Wang, Ye; Gao, Xiang; Zuo, Jian; Zhu, Min-Sheng; Gao, Xia; Wan, Guoqiang.
Afiliação
  • Zhu GJ; Department of Otorhinolaryngology, Provincial Key Discipline of the affiliated Drum Tower Hospital of Nanjing University and Model Animal Research Center, MOE Key Laboratory of Model Animal for Disease Studies, School of Medicine, Nanjing University, Nanjing, China.
  • Gong S; Department of Otorhinolaryngology, Provincial Key Discipline of the affiliated Drum Tower Hospital of Nanjing University and Model Animal Research Center, MOE Key Laboratory of Model Animal for Disease Studies, School of Medicine, Nanjing University, Nanjing, China.
  • Ma DB; Department of Otorhinolaryngology, Provincial Key Discipline of the affiliated Drum Tower Hospital of Nanjing University and Model Animal Research Center, MOE Key Laboratory of Model Animal for Disease Studies, School of Medicine, Nanjing University, Nanjing, China.
  • Tao T; Department of Otorhinolaryngology, Provincial Key Discipline of the affiliated Drum Tower Hospital of Nanjing University and Model Animal Research Center, MOE Key Laboratory of Model Animal for Disease Studies, School of Medicine, Nanjing University, Nanjing, China.
  • He WQ; Department of Otorhinolaryngology, Provincial Key Discipline of the affiliated Drum Tower Hospital of Nanjing University and Model Animal Research Center, MOE Key Laboratory of Model Animal for Disease Studies, School of Medicine, Nanjing University, Nanjing, China.
  • Zhang L; Jiangsu Key Laboratory of Neuropsychiatric Diseases and Cambridge-Suda (CAM-SU) Genomic Resource Center, Medical College of Soochow University, Suzhou, China.
  • Wang F; Department of Otorhinolaryngology, Provincial Key Discipline of the affiliated Drum Tower Hospital of Nanjing University and Model Animal Research Center, MOE Key Laboratory of Model Animal for Disease Studies, School of Medicine, Nanjing University, Nanjing, China.
  • Qian XY; Department of Otorhinolaryngology, Provincial Key Discipline of the affiliated Drum Tower Hospital of Nanjing University and Model Animal Research Center, MOE Key Laboratory of Model Animal for Disease Studies, School of Medicine, Nanjing University, Nanjing, China.
  • Zhou H; Department of Otorhinolaryngology, Provincial Key Discipline of the affiliated Drum Tower Hospital of Nanjing University and Model Animal Research Center, MOE Key Laboratory of Model Animal for Disease Studies, School of Medicine, Nanjing University, Nanjing, China.
  • Fan C; Department of Otorhinolaryngology, Provincial Key Discipline of the affiliated Drum Tower Hospital of Nanjing University and Model Animal Research Center, MOE Key Laboratory of Model Animal for Disease Studies, School of Medicine, Nanjing University, Nanjing, China.
  • Wang P; Department of Otorhinolaryngology, Provincial Key Discipline of the affiliated Drum Tower Hospital of Nanjing University and Model Animal Research Center, MOE Key Laboratory of Model Animal for Disease Studies, School of Medicine, Nanjing University, Nanjing, China.
  • Chen X; Department of Otorhinolaryngology, Provincial Key Discipline of the affiliated Drum Tower Hospital of Nanjing University and Model Animal Research Center, MOE Key Laboratory of Model Animal for Disease Studies, School of Medicine, Nanjing University, Nanjing, China.
  • Zhao W; Department of Otorhinolaryngology, Provincial Key Discipline of the affiliated Drum Tower Hospital of Nanjing University and Model Animal Research Center, MOE Key Laboratory of Model Animal for Disease Studies, School of Medicine, Nanjing University, Nanjing, China.
  • Sun J; Department of Otorhinolaryngology, Provincial Key Discipline of the affiliated Drum Tower Hospital of Nanjing University and Model Animal Research Center, MOE Key Laboratory of Model Animal for Disease Studies, School of Medicine, Nanjing University, Nanjing, China.
  • Chen H; Department of Otorhinolaryngology, Provincial Key Discipline of the affiliated Drum Tower Hospital of Nanjing University and Model Animal Research Center, MOE Key Laboratory of Model Animal for Disease Studies, School of Medicine, Nanjing University, Nanjing, China.
  • Wang Y; College of Life Science, Nanjing Normal University, Nanjing, China.
  • Gao X; Nanjing MuCyte Biotechnology Co., Ltd., Nanjing, China.
  • Zuo J; Department of Otorhinolaryngology, Provincial Key Discipline of the affiliated Drum Tower Hospital of Nanjing University and Model Animal Research Center, MOE Key Laboratory of Model Animal for Disease Studies, School of Medicine, Nanjing University, Nanjing, China.
  • Zhu MS; Department of Biomedical Sciences, School of Medicine, Creighton University, United States of America.
  • Gao X; Department of Otorhinolaryngology, Provincial Key Discipline of the affiliated Drum Tower Hospital of Nanjing University and Model Animal Research Center, MOE Key Laboratory of Model Animal for Disease Studies, School of Medicine, Nanjing University, Nanjing, China.
  • Wan G; Institute for Brain Sciences, Nanjing University, Nanjing, China.
PLoS Genet ; 16(9): e1009040, 2020 09.
Article em En | MEDLINE | ID: mdl-32970669

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Proteínas de Homeodomínio / Aldeído Desidrogenase / Inibidores Enzimáticos / Fator de Transcrição Brn-3C / Células Ciliadas Auditivas / Perda Auditiva Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: PLoS Genet Assunto da revista: GENETICA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Proteínas de Homeodomínio / Aldeído Desidrogenase / Inibidores Enzimáticos / Fator de Transcrição Brn-3C / Células Ciliadas Auditivas / Perda Auditiva Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: PLoS Genet Assunto da revista: GENETICA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China