What is hiden behind autoinflammation?
Vnitr Lek
; 66(3): 35-43, 2020.
Article
em En
| MEDLINE
| ID: mdl-32972163
ABSTRACT
Autoinflammatory diseases represent a group of disorders that are distinct from autoimmune diseases, infections and malignancies. They are characterised by attacks of unprovoked noninfectious inflammation. A key feature of autoinflammatory diseases is dysregulation of innate immune system and overproduction of pro-inflammatory cytokines. The best-characterized group of autoinflammatory diseases arises from mutations in single genes. They are typically manifested by recurrent attacks of fever and serositis as well as arthralgia, myalgia and skin exanthema.
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Bases de dados:
MEDLINE
Assunto principal:
Doenças Autoimunes
/
Doenças Hereditárias Autoinflamatórias
Limite:
Humans
Idioma:
En
Revista:
Vnitr Lek
Ano de publicação:
2020
Tipo de documento:
Article