The therapeutic effect of the BRD4-degrading PROTAC A1874 in human colon cancer cells.

Qin, An-Cheng; Jin, Hua; Song, Yu; Gao, Yun; Chen, Yi-Fan; Zhou, Li-Na; Wang, Shu-Sheng; Lu, Xing-Sheng

Qin, An-Cheng; Jin, Hua; Song, Yu; Gao, Yun; Chen, Yi-Fan; Zhou, Li-Na; Wang, Shu-Sheng; Lu, Xing-Sheng.

Afiliação

Qin AC; Department of Hepatobiliary Surgery, Suzhou Municipal Hospital Affiliated to Nanjing Medical University, Suzhou, China.
Jin H; The Child Health Care Department, Suzhou Ninth People's Hospital, Suzhou, China.
Song Y; Department of Oncology, The Affiliated Zhangjiagang Hospital of Soochow University, Suzhou, China.
Gao Y; Trauma center, Affiliated Hospital of Yangzhou University, Yangzhou, China.
Chen YF; Department of Hepatobiliary Surgery, Suzhou Municipal Hospital Affiliated to Nanjing Medical University, Suzhou, China.
Zhou LN; Department of Radiotherapy and Oncology, Affiliated Kunshan Hospital of Jiangsu University, Kunshan, China. zhoulinaks@163.com.
Wang SS; Department of General Surgery, The Affiliated Zhangjiagang Hospital of Soochow University, Suzhou, China. drwangsszjg@163.com.
Lu XS; Department of Hepatobiliary Surgery, Suzhou Municipal Hospital Affiliated to Nanjing Medical University, Suzhou, China. drluxsslyy@163.com.

Cell Death Dis ; 11(9): 805, 2020 09 25.

Article em En | MEDLINE | ID: mdl-32978368

Assuntos

Neoplasias do Colo/genética; Proteínas Nucleares/metabolismo; Fatores de Transcrição/metabolismo; Animais; Apoptose; Feminino; Humanos; Camundongos; Camundongos SCID; Oncogenes

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Fatores de Transcrição / Proteínas Nucleares / Neoplasias do Colo Limite: Animals / Female / Humans Idioma: En Revista: Cell Death Dis Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China

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