Astragaloside IV Derivative (LS-102) Alleviated Myocardial Ischemia Reperfusion Injury by Inhibiting Drp1<sup>Ser616</sup> Phosphorylation-Mediated Mitochondrial Fission.

Chen, Li; Chen, Xiao-Yi; Wang, Qian-Long; Yang, Si-Jin; Zhou, Hua; Ding, Li-Sheng; Qing, Lin-Sen; Luo, Pei

Astragaloside IV Derivative (LS-102) Alleviated Myocardial Ischemia Reperfusion Injury by Inhibiting Drp1^Ser616 Phosphorylation-Mediated Mitochondrial Fission.

Chen, Li; Chen, Xiao-Yi; Wang, Qian-Long; Yang, Si-Jin; Zhou, Hua; Ding, Li-Sheng; Qing, Lin-Sen; Luo, Pei.

Afiliação

Chen L; State Key Laboratories for Quality Research in Chinese Medicines, Macau University of Science and Technology, Macau, China.
Chen XY; Department of Cardiac Encephalopathy, Traditional Chinese Medicine Hospital Affiliated to Southwest Medical University, Luzhou, China.
Wang QL; State Key Laboratories for Quality Research in Chinese Medicines, Macau University of Science and Technology, Macau, China.
Yang SJ; State Key Laboratories for Quality Research in Chinese Medicines, Macau University of Science and Technology, Macau, China.
Zhou H; Department of Cardiac Encephalopathy, Traditional Chinese Medicine Hospital Affiliated to Southwest Medical University, Luzhou, China.
Ding LS; State Key Laboratories for Quality Research in Chinese Medicines, Macau University of Science and Technology, Macau, China.
Qing LS; Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, China.
Luo P; Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, China.

Front Pharmacol ; 11: 1083, 2020.

Article em En | MEDLINE | ID: mdl-33041784

Palavras-chave

Drp1 phosphorylation; GSK-3ß; astragalosidic acid; mitochondrial fission; myocardial ischemia reperfusion

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Texto completo: 1 Bases de dados: MEDLINE Idioma: En Revista: Front Pharmacol Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China