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First-in-Human Phase I Study of Iadademstat (ORY-1001): A First-in-Class Lysine-Specific Histone Demethylase 1A Inhibitor, in Relapsed or Refractory Acute Myeloid Leukemia.
Salamero, Olga; Montesinos, Pau; Willekens, Christophe; Pérez-Simón, José Antonio; Pigneux, Arnaud; Récher, Christian; Popat, Rakesh; Carpio, Cecilia; Molinero, César; Mascaró, Cristina; Vila, Joaquim; Arévalo, M Isabel; Maes, Tamara; Buesa, Carlos; Bosch, Francesc; Somervaille, Tim C P.
Afiliação
  • Salamero O; Hospital Vall d'Hebron, Vall D'Hebron Institute of Oncology, Departament de Medicina, Universitat Autònoma de Barcelona, UAB, Barcelona, Spain.
  • Montesinos P; Hospital Universitari I Politécnic La Fe, València, Spain.
  • Willekens C; Centro de Investigación Biomédica en Red de Cáncer, Instituto Carlos III, Madrid, Spain.
  • Pérez-Simón JA; Institut Gustave Roussy, Villejuif Cedex, France.
  • Pigneux A; Hospital Universitario Virgen del Rocío, Sevilla, Spain.
  • Récher C; Instituto de Biomedicina de Sevilla (Insitituto de Biomedicina De Sevilla/Consejo Superior De Investigaciones Científicas/Centro de Investigación Biomédica en Red de Cáncer), Universidad de Sevilla, Sevilla, Spain.
  • Popat R; Centre Hospitalier Universitaire CHU Bordeaux, Hôpital du Haut Lévêque, Pessac, France.
  • Carpio C; Hospitalier Universitaire de Toulouse, Institut Universitaire du Cancer de Toulouse Oncopole, Université Toulouse III Paul Sabatier, Toulouse, France.
  • Molinero C; National Institute for Health Research UCLH Clinical Research Facility, University College London Hospitals NHS Foundation Trust, London, United Kingdom.
  • Mascaró C; Hospital Vall d'Hebron, Vall D'Hebron Institute of Oncology, Departament de Medicina, Universitat Autònoma de Barcelona, UAB, Barcelona, Spain.
  • Vila J; Oryzon Genomics, Barcelona, Spain.
  • Arévalo MI; Oryzon Genomics, Barcelona, Spain.
  • Maes T; Oryzon Genomics, Barcelona, Spain.
  • Buesa C; Oryzon Genomics, Barcelona, Spain.
  • Bosch F; Oryzon Genomics, Barcelona, Spain.
  • Somervaille TCP; Oryzon Genomics, Barcelona, Spain.
J Clin Oncol ; 38(36): 4260-4273, 2020 12 20.
Article em En | MEDLINE | ID: mdl-33052756
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Inibidores Enzimáticos / Histona Desmetilases Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: J Clin Oncol Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Espanha
Texto completo
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Imprimir
XML
PubMed Links
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Inibidores Enzimáticos / Histona Desmetilases Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: J Clin Oncol Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Espanha