Efficacy of Surgical Excision and Brachytherapy in the Treatment of Keloids: A Retrospective Cohort Study.
Adv Skin Wound Care
; 33(11): 1-6, 2020 Nov.
Article
em En
| MEDLINE
| ID: mdl-33065689
ABSTRACT
OBJECTIVE:
To demonstrate the efficacy of a protocol combining surgical excision and high-dose-rate brachytherapy for treatment of keloids.METHODS:
The authors performed a unicentric retrospective cohort study between 2013 and 2018. The minimum follow-up was 12 months. All patients treated for keloids at the authors' institution were included. Extralesional excision was performed with placement of a brachytherapy sheath under the skin. The total dose of irradiation was 18 Gy. The postoperative results were evaluated for aesthetic and functional outcomes with a validated scale, as well as the presence or absence of recurrence.RESULTS:
Fifteen patients were lost to follow-up. Thirty-eight patients with 67 keloids were included. The control rate was 94%. The aesthetic and functional outcomes were considered good in 62% of cases. The main limitation of the study was the small patient population.CONCLUSIONS:
Extralesional excision combined with postoperative high-dose-rate brachytherapy seems to be one of the most effective invasive protocols to treat and prevent keloids.
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Braquiterapia
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Criocirurgia
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Procedimentos Cirúrgicos Dermatológicos
/
Queloide
Tipo de estudo:
Etiology_studies
/
Guideline
/
Observational_studies
/
Prognostic_studies
Limite:
Adult
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Adv Skin Wound Care
Assunto da revista:
ENFERMAGEM
Ano de publicação:
2020
Tipo de documento:
Article