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Investigation of pH-Responsiveness inside Lipid Nanoparticles for Parenteral mRNA Application Using Small-Angle X-ray Scattering.
Uebbing, Lukas; Ziller, Antje; Siewert, Christian; Schroer, Martin A; Blanchet, Clement E; Svergun, Dmitri I; Ramishetti, Srinivas; Peer, Dan; Sahin, Ugur; Haas, Heinrich; Langguth, Peter.
Afiliação
  • Uebbing L; Department of Pharmaceutics and Biopharmaceutics, Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University Mainz, Staudingerweg 5, D-55099 Mainz, Germany.
  • Ziller A; Department of Pharmaceutics and Biopharmaceutics, Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University Mainz, Staudingerweg 5, D-55099 Mainz, Germany.
  • Siewert C; Department of Pharmaceutics and Biopharmaceutics, Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University Mainz, Staudingerweg 5, D-55099 Mainz, Germany.
  • Schroer MA; European Molecular Biology Laboratory (EMBL) Hamburg Outstation c/o DESY, 22607 Hamburg, Germany.
  • Blanchet CE; European Molecular Biology Laboratory (EMBL) Hamburg Outstation c/o DESY, 22607 Hamburg, Germany.
  • Svergun DI; European Molecular Biology Laboratory (EMBL) Hamburg Outstation c/o DESY, 22607 Hamburg, Germany.
  • Ramishetti S; Laboratory of Precision NanoMedicine, Shmunis School for Biomedicine and Cancer Research, George S. Wise Faculty of Life Sciences, Tel Aviv University, P.O. Box 39040, Tel Aviv 69978, Israel.
  • Peer D; Laboratory of Precision NanoMedicine, Shmunis School for Biomedicine and Cancer Research, George S. Wise Faculty of Life Sciences, Tel Aviv University, P.O. Box 39040, Tel Aviv 69978, Israel.
  • Sahin U; BioNTech RNA Pharmaceuticals GmbH, An der Goldgrube 12, 55131 Mainz, Germany.
  • Haas H; TRON - Translational Oncology at the University Medical Center of Johannes Gutenberg University Mainz gGmbH, 55099 Mainz, Germany.
  • Langguth P; Research Center for Immunotherapy (FZI), University Medical Center at the Johannes Gutenberg University Mainz, 55099 Mainz, Germany.
Langmuir ; 36(44): 13331-13341, 2020 11 10.
Article em En | MEDLINE | ID: mdl-33108188

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Nanopartículas Idioma: En Revista: Langmuir Assunto da revista: QUIMICA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Alemanha

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Nanopartículas Idioma: En Revista: Langmuir Assunto da revista: QUIMICA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Alemanha