Heat Shock Protein 90 Inhibitors AUY922, BIIB021 and SNX5422 Induce Bim-mediated Death of Thyroid Carcinoma Cells.

Kim, Si Hyoung; Cho, Yun Kyung; Huh, Ji Hye; Kang, Jun Goo; Ihm, Sung-Hee; Choi, Moon Gi; Lee, Seong Jin

Kim, Si Hyoung; Cho, Yun Kyung; Huh, Ji Hye; Kang, Jun Goo; Ihm, Sung-Hee; Choi, Moon Gi; Lee, Seong Jin.

Afiliação

Kim SH; Division of Endocrinology and Metabolism, Department of Internal Medicine, College of Medicine, Hallym University, Chuncheon, Republic of Korea.
Cho YK; Division of Endocrinology and Metabolism, Department of Internal Medicine, College of Medicine, Hallym University, Chuncheon, Republic of Korea.
Huh JH; Division of Endocrinology and Metabolism, Department of Internal Medicine, College of Medicine, Hallym University, Chuncheon, Republic of Korea.
Kang JG; Division of Endocrinology and Metabolism, Department of Internal Medicine, College of Medicine, Hallym University, Chuncheon, Republic of Korea.
Ihm SH; Division of Endocrinology and Metabolism, Department of Internal Medicine, College of Medicine, Hallym University, Chuncheon, Republic of Korea.
Choi MG; Division of Endocrinology and Metabolism, Department of Internal Medicine, College of Medicine, Hallym University, Chuncheon, Republic of Korea.
Lee SJ; Division of Endocrinology and Metabolism, Department of Internal Medicine, College of Medicine, Hallym University, Chuncheon, Republic of Korea leesj@hallym.ac.kr.

Anticancer Res ; 40(11): 6137-6150, 2020 Nov.

Article em En | MEDLINE | ID: mdl-33109551

Assuntos

Adenina/análogos & derivados; Apoptose/efeitos dos fármacos; Proteína 11 Semelhante a Bcl-2/metabolismo; Benzamidas/farmacologia; Proteínas de Choque Térmico HSP90/antagonistas & inibidores; Indazóis/farmacologia; Isoxazóis/farmacologia; Piridinas/farmacologia; Resorcinóis/farmacologia; Neoplasias da Glândula Tireoide/patologia; Adenina/farmacologia; Linhagem Celular Tumoral; Sobrevivência Celular/efeitos dos fármacos; MAP Quinases Reguladas por Sinal Extracelular/metabolismo; Glicina; Proteínas de Choque Térmico HSP90/metabolismo; Humanos; Proteínas Proto-Oncogênicas c-akt/metabolismo; Transdução de Sinais/efeitos dos fármacos; Neoplasias da Glândula Tireoide/enzimologia

Palavras-chave

AUY922; BIIB021; Bim; HSP90 inhibitor; SNX5422; Thyroid carcinoma

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Piridinas / Resorcinóis / Benzamidas / Neoplasias da Glândula Tireoide / Adenina / Apoptose / Proteínas de Choque Térmico HSP90 / Proteína 11 Semelhante a Bcl-2 / Indazóis / Isoxazóis Limite: Humans Idioma: En Revista: Anticancer Res Ano de publicação: 2020 Tipo de documento: Article

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