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Synthesis and Pharmacology of a Novel µ-δ Opioid Receptor Heteromer-Selective Agonist Based on the Carfentanyl Template.
Faouzi, Abdelfattah; Uprety, Rajendra; Gomes, Ivone; Massaly, Nicolas; Keresztes, Attila I; Le Rouzic, Valerie; Gupta, Achla; Zhang, Tiffany; Yoon, Hye Jean; Ansonoff, Michael; Allaoa, Abdullah; Pan, Ying Xian; Pintar, John; Morón, Jose A; Streicher, John M; Devi, Lakshmi A; Majumdar, Susruta.
Afiliação
  • Faouzi A; Center for Clinical Pharmacology, St Louis College of Pharmacy and Washington University, School of Medicine, St. Louis, Missouri 63110, United States.
  • Uprety R; Department of Anesthesiology, Washington University School of Medicine, St. Louis, Missouri 63110, United States.
  • Gomes I; Department of Neurology and Molecular Pharmacology, Memorial Sloan Kettering Cancer Center, New York, New York 10065, United States.
  • Massaly N; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States.
  • Keresztes AI; Department of Anesthesiology, Washington University School of Medicine, St. Louis, Missouri 63110, United States.
  • Le Rouzic V; Department of Pharmacology, College of Medicine, University of Arizona, Tucson, Arkansas 85724, United States.
  • Gupta A; Department of Neurology and Molecular Pharmacology, Memorial Sloan Kettering Cancer Center, New York, New York 10065, United States.
  • Zhang T; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States.
  • Yoon HJ; Department of Neurology and Molecular Pharmacology, Memorial Sloan Kettering Cancer Center, New York, New York 10065, United States.
  • Ansonoff M; Department of Anesthesiology, Washington University School of Medicine, St. Louis, Missouri 63110, United States.
  • Allaoa A; Department of Neuroscience and Cell Biology, Rutgers Robert Wood Johnson Medical School, Piscataway, New Jersey 08854, United States.
  • Pan YX; Department of Neurology and Molecular Pharmacology, Memorial Sloan Kettering Cancer Center, New York, New York 10065, United States.
  • Pintar J; Department of Neurology and Molecular Pharmacology, Memorial Sloan Kettering Cancer Center, New York, New York 10065, United States.
  • Morón JA; Department of Neuroscience and Cell Biology, Rutgers Robert Wood Johnson Medical School, Piscataway, New Jersey 08854, United States.
  • Streicher JM; Department of Anesthesiology, Washington University School of Medicine, St. Louis, Missouri 63110, United States.
  • Devi LA; Department of Neuroscience and Psychiatry, Washington University School of Medicine, St. Louis, Missouri 63110, United States.
  • Majumdar S; Department of Pharmacology, College of Medicine, University of Arizona, Tucson, Arkansas 85724, United States.
J Med Chem ; 63(22): 13618-13637, 2020 11 25.
Article em En | MEDLINE | ID: mdl-33170687

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Fentanila / Receptores Opioides delta Limite: Animals / Humans / Male Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Fentanila / Receptores Opioides delta Limite: Animals / Humans / Male Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos