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Mdr1a, Bcrp and Mrp2 regulate the efficacy and toxicity of mesaconitine and hypaconitine by altering their tissue accumulation and in vivo residence.
Li, Xiaocui; Ou, Xiaowen; Luo, Guangkuo; Ou, Xiaojun; Xie, Yushan; Ying, Mengdi; Qu, Wei; Zuo, Huilin; Qi, Xiaoxiao; Wang, Ying; Liu, Zhongqiu; Zhu, Lijun.
Afiliação
  • Li X; International Institute for Translational Chinese Medicine, School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province 510006, PR China.
  • Ou X; International Institute for Translational Chinese Medicine, School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province 510006, PR China.
  • Luo G; International Institute for Translational Chinese Medicine, School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province 510006, PR China.
  • Ou X; International Institute for Translational Chinese Medicine, School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province 510006, PR China.
  • Xie Y; International Institute for Translational Chinese Medicine, School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province 510006, PR China.
  • Ying M; International Institute for Translational Chinese Medicine, School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province 510006, PR China.
  • Qu W; International Institute for Translational Chinese Medicine, School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province 510006, PR China.
  • Zuo H; International Institute for Translational Chinese Medicine, School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province 510006, PR China.
  • Qi X; International Institute for Translational Chinese Medicine, School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province 510006, PR China.
  • Wang Y; International Institute for Translational Chinese Medicine, School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province 510006, PR China.
  • Liu Z; International Institute for Translational Chinese Medicine, School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province 510006, PR China. Electronic address: liuzq@gzucm.edu.cn.
  • Zhu L; International Institute for Translational Chinese Medicine, School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province 510006, PR China. Electronic address: zhulijun@gzucm.edu.cn.
Toxicol Appl Pharmacol ; 409: 115332, 2020 12 15.
Article em En | MEDLINE | ID: mdl-33171190
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Aconitina / Subfamília B de Transportador de Cassetes de Ligação de ATP / Proteínas Associadas à Resistência a Múltiplos Medicamentos / Membro 2 da Subfamília G de Transportadores de Cassetes de Ligação de ATP Limite: Animals Idioma: En Revista: Toxicol Appl Pharmacol Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Aconitina / Subfamília B de Transportador de Cassetes de Ligação de ATP / Proteínas Associadas à Resistência a Múltiplos Medicamentos / Membro 2 da Subfamília G de Transportadores de Cassetes de Ligação de ATP Limite: Animals Idioma: En Revista: Toxicol Appl Pharmacol Ano de publicação: 2020 Tipo de documento: Article