Ocular Surface - Merging Challenges and Opportunities.
Transl Vis Sci Technol
; 9(12): 3, 2020 11.
Article
em En
| MEDLINE
| ID: mdl-33200045
ABSTRACT
Dichotomies are double-edged they can simplify and enlighten as well as exaggerate and entangle. Seeing the eye as anterior segment vs. posterior segment simplifies the formidable task of dissecting the function of the eye. Yet this view creates artificial divisions in a coherent whole. Clearly, vision requires the convergence of the light refractive function of the front of the eye with the light sensing function of the back of the eye. The National Eye Institute has long aimed to foster research across the visual pathway. Finding the right balance is a constant work in progress. A recently held scientific meeting which we co-organized with the United States Army Medical Research Institute of Chemical Defense, offered an opportunity to take stock of what the anterior segment in general, and the ocular surface in particular, bring to our understanding of biology and disease of the eye. Multiple dichotomies surfaced acute vs. chronic disease; epithelial vs. endothelial damage; fibrotic vs. vascular pathology; inflammation vs. resolution response; chemical exposure vs. countermeasure; monotherapy vs. combination therapy; mechanistic vs. exploratory research; human vs. animal model. Merging some of these dichotomies is the goal of this paper.
Palavras-chave
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Segmento Anterior do Olho
Tipo de estudo:
Prognostic_studies
Limite:
Animals
/
Humans
País/Região como assunto:
America do norte
Idioma:
En
Revista:
Transl Vis Sci Technol
Ano de publicação:
2020
Tipo de documento:
Article
País de afiliação:
Estados Unidos