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Discovery of highly selective and orally available benzimidazole-based phosphodiesterase 10 inhibitors with improved solubility and pharmacokinetic properties for treatment of pulmonary arterial hypertension.
Yang, Yuncong; Zhang, Sirui; Zhou, Qian; Zhang, Chen; Gao, Yuqi; Wang, Hao; Li, Zhe; Wu, Deyan; Wu, Yinuo; Huang, Yi-You; Guo, Lei; Luo, Hai-Bin.
Afiliação
  • Yang Y; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
  • Zhang S; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
  • Zhou Q; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
  • Zhang C; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
  • Gao Y; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
  • Wang H; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
  • Li Z; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
  • Wu D; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
  • Wu Y; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
  • Huang YY; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
  • Guo L; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
  • Luo HB; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
Acta Pharm Sin B ; 10(12): 2339-2347, 2020 Dec.
Article em En | MEDLINE | ID: mdl-33354505
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Texto completo: 1 Bases de dados: MEDLINE Tipo de estudo: Guideline Idioma: En Revista: Acta Pharm Sin B Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Bases de dados: MEDLINE Tipo de estudo: Guideline Idioma: En Revista: Acta Pharm Sin B Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China