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Cobalt Bis(dicarbollide) Alkylsulfonamides: Potent and Highly Selective Inhibitors of Tumor Specific Carbonic Anhydrase IX.
Grüner, Bohumír; Kugler, Michael; El Anwar, Suzan; Holub, Josef; Nekvinda, Jan; Bavol, Dmytro; Ruzicková, Zdenka; Pospísilová, Klára; Fábry, Milan; Král, Vlastimil; Brynda, Jirí; Rezácová, Pavlína.
Afiliação
  • Grüner B; Department of Synthesis, Institute of Inorganic Chemistry of the Czech Academy of Sciences, 250 68, Rez, Czech Republic.
  • Kugler M; Institute of Molecular Genetics of the Czech Academy of Sciences, Vídenská 1083, 142 20, Prague 4, Czech Republic.
  • El Anwar S; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo nám. 2, 166 10, Prague, Czech Republic.
  • Holub J; Department of Synthesis, Institute of Inorganic Chemistry of the Czech Academy of Sciences, 250 68, Rez, Czech Republic.
  • Nekvinda J; Department of Synthesis, Institute of Inorganic Chemistry of the Czech Academy of Sciences, 250 68, Rez, Czech Republic.
  • Bavol D; Department of Synthesis, Institute of Inorganic Chemistry of the Czech Academy of Sciences, 250 68, Rez, Czech Republic.
  • Ruzicková Z; Department of Synthesis, Institute of Inorganic Chemistry of the Czech Academy of Sciences, 250 68, Rez, Czech Republic.
  • Pospísilová K; Department of General and Inorganic Chemistry, Faculty of Chemical Technology, University of Pardubice, Studentská 573, 532 10, Pardubice, Czech Republic.
  • Fábry M; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo nám. 2, 166 10, Prague, Czech Republic.
  • Král V; Institute of Molecular Genetics of the Czech Academy of Sciences, Vídenská 1083, 142 20, Prague 4, Czech Republic.
  • Brynda J; Institute of Molecular Genetics of the Czech Academy of Sciences, Vídenská 1083, 142 20, Prague 4, Czech Republic.
  • Rezácová P; Institute of Molecular Genetics of the Czech Academy of Sciences, Vídenská 1083, 142 20, Prague 4, Czech Republic.
Chempluschem ; 86(3): 351, 2021 03.
Article em En | MEDLINE | ID: mdl-33369232
Invited for this month's cover is a collaboration from three institutes from the Czech Academy of Sciences: Institute of Inorganic Chemistry, Institute of Organic Chemistry and Biochemistry, and Institute of Molecular Genetics, and the University of Pardubice. The cover picture shows a family of potent and selective CA IX inhibitors that combines the structural motif of a bulky inorganic cobalt bis(dicarbollide) polyhedral ion with a propylsulfonamido anchor group. Read the full text of the article at 10.1002/cplu.202000574.
Assuntos

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Inibidores da Anidrase Carbônica / Neoplasias Limite: Humans Idioma: En Revista: Chempluschem Ano de publicação: 2021 Tipo de documento: Article País de afiliação: República Tcheca

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Inibidores da Anidrase Carbônica / Neoplasias Limite: Humans Idioma: En Revista: Chempluschem Ano de publicação: 2021 Tipo de documento: Article País de afiliação: República Tcheca