Acriflavine, a Potent Inhibitor of HIF-1&#945;, Disturbs Glucose Metabolism and Suppresses ATF4-Protective Pathways in Melanoma under Non-Hypoxic Conditions.

Martí-Díaz, Román; Montenegro, María F; Cabezas-Herrera, Juan; Goding, Colin R; Rodríguez-López, José Neptuno; Sánchez-Del-Campo, Luis

Acriflavine, a Potent Inhibitor of HIF-1α, Disturbs Glucose Metabolism and Suppresses ATF4-Protective Pathways in Melanoma under Non-Hypoxic Conditions.

Martí-Díaz, Román; Montenegro, María F; Cabezas-Herrera, Juan; Goding, Colin R; Rodríguez-López, José Neptuno; Sánchez-Del-Campo, Luis.

Afiliação

Martí-Díaz R; Department of Biochemistry and Molecular Biology A, School of Biology, IMIB-University of Murcia, 30100 Murcia, Spain.
Montenegro MF; Department of Biochemistry and Molecular Biology A, School of Biology, IMIB-University of Murcia, 30100 Murcia, Spain.
Cabezas-Herrera J; Translational Cancer Research Group, University Hospital Virgen de la Arrixaca, IMIB, 30120 Murcia, Spain.
Goding CR; Ludwig Institute for Cancer Research, Nuffield Department of Clinical Medicine, University of Oxford, Headington, Oxford OX3 7DQ, UK.
Rodríguez-López JN; Department of Biochemistry and Molecular Biology A, School of Biology, IMIB-University of Murcia, 30100 Murcia, Spain.
Sánchez-Del-Campo L; Department of Biochemistry and Molecular Biology A, School of Biology, IMIB-University of Murcia, 30100 Murcia, Spain.

Cancers (Basel) ; 13(1)2020 Dec 31.

Article em En | MEDLINE | ID: mdl-33396270

Palavras-chave

ATF4; HIF-1α; MITF; acriflavine; glucose metabolism; melanoma; oxygen homeostasis

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Texto completo: 1 Bases de dados: MEDLINE Idioma: En Revista: Cancers (Basel) Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Espanha