SZR-104, a Novel Kynurenic Acid Analogue with High Permeability through the Blood-Brain Barrier.

Molnár, Kinga; Lorinczi, Bálint; Fazakas, Csilla; Szatmári, István; Fülöp, Ferenc; Kmetykó, Noémi; Berkecz, Róbert; Ilisz, István; Krizbai, István A; Wilhelm, Imola; Vécsei, László

Molnár, Kinga; Lorinczi, Bálint; Fazakas, Csilla; Szatmári, István; Fülöp, Ferenc; Kmetykó, Noémi; Berkecz, Róbert; Ilisz, István; Krizbai, István A; Wilhelm, Imola; Vécsei, László.

Afiliação

Molnár K; Institute of Biophysics, Biological Research Centre, 6726 Szeged, Hungary.
Lorinczi B; Theoretical Medicine Doctoral School, University of Szeged, 6720 Szeged, Hungary.
Fazakas C; Institute of Pharmaceutical Chemistry and Research Group for Stereochemistry, Hungarian Academy of Sciences, University of Szeged, 6720 Szeged, Hungary.
Szatmári I; Institute of Pharmaceutical Chemistry, Interdisciplinary Excellence Center, University of Szeged, 6720 Szeged, Hungary.
Fülöp F; Institute of Biophysics, Biological Research Centre, 6726 Szeged, Hungary.
Kmetykó N; Institute of Pharmaceutical Chemistry and Research Group for Stereochemistry, Hungarian Academy of Sciences, University of Szeged, 6720 Szeged, Hungary.
Berkecz R; Institute of Pharmaceutical Chemistry, Interdisciplinary Excellence Center, University of Szeged, 6720 Szeged, Hungary.
Ilisz I; Institute of Pharmaceutical Chemistry and Research Group for Stereochemistry, Hungarian Academy of Sciences, University of Szeged, 6720 Szeged, Hungary.
Krizbai IA; Institute of Pharmaceutical Chemistry, Interdisciplinary Excellence Center, University of Szeged, 6720 Szeged, Hungary.
Wilhelm I; Institute of Pharmaceutical Analysis, Interdisciplinary Excellence Center, University of Szeged, 6720 Szeged, Hungary.
Vécsei L; Institute of Pharmaceutical Analysis, Interdisciplinary Excellence Center, University of Szeged, 6720 Szeged, Hungary.

Pharmaceutics ; 13(1)2021 Jan 05.

Article em En | MEDLINE | ID: mdl-33466551

Palavras-chave

SZR-104; aminoalkylated amide derivatives; bloodbrain barrier (BBB); in vitro model; kynurenic acid (KYNA); permeability

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Texto completo: 1 Bases de dados: MEDLINE Idioma: En Revista: Pharmaceutics Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Hungria