Predictors of quality of life in allogeneic hematopoietic stem cell transplantation survivors.
J Psychosoc Oncol
; 39(4): 534-552, 2021.
Article
em En
| MEDLINE
| ID: mdl-33468039
ABSTRACT
OBJECTIVES:
To establish the demographic, medical, transplant, and lifestyle factors that impact Quality of Life (QoL) in long-term survivors of allogeneic Hematopoietic Stem Cell Transplantation (allo-HSCT).DESIGN:
Cross-sectional study utilizing self-report measures. SAMPLE/METHODS:
In this cross-sectional study of 441 adult survivors of allo-HSCT, participants completed questionnaires assessing QoL, psychological, social, demographic, and clinical variables.FINDINGS:
Factors associated with improved QoL post-allo-HSCT included time since transplant, female gender, attendance at outpatient appointments, health screening uptake, exercise, and resumption of travel. Factors significantly associated with impaired QoL included chronic morbidities (GVHD), taking psychotropic medication, failure to resume sexual activity (in men), male gender, psychological distress, low income or decline in work status, transition to non-physical work, and necessity for post-allo-HSCT care from various health professionals. IMPLICATIONS FOR PSYCHOSOCIAL PROVIDERS Identification of survivors more likely to experience a reduced QoL following allo-HSCT may enable the targeting of health services to the most vulnerable, and the development of interventions and resources. The data from this study led to the development of HSCT Long-Term Follow Up Clinical Guidelines in New South Wales.Palavras-chave
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Qualidade de Vida
/
Transplante de Células-Tronco Hematopoéticas
Tipo de estudo:
Guideline
/
Observational_studies
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Prevalence_studies
/
Prognostic_studies
/
Qualitative_research
/
Risk_factors_studies
Limite:
Female
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Humans
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Male
Idioma:
En
Revista:
J Psychosoc Oncol
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Austrália