Control and isotopic quantification of affinity of antithrombin III for heparin-like surfaces.
Biomaterials
; 9(1): 62-5, 1988 Jan.
Article
em En
| MEDLINE
| ID: mdl-3349123
ABSTRACT
Heparin-like materials, characterized by a defined superficial density of functional groups which activate antithrombin III (AT III), when in contact with blood specifically inhibit thrombin as soon as it appears. This paper describes an isotopic method to estimate this density and to visualize the distribution of the affinity sites concerned, both directly with AT III labelled with 125Iodine and indirectly with an anti AT III monoclonal antibody labelled with 111Indium.
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Bases de dados:
MEDLINE
Assunto principal:
Materiais Biocompatíveis
/
Heparina
/
Antitrombina III
Idioma:
En
Revista:
Biomaterials
Ano de publicação:
1988
Tipo de documento:
Article
País de afiliação:
França