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The DESolve® novolimus bioresorbable scaffold.
Demola, Pierluigi; Meucci, Francesco; Stolcova, Miroslava; Mario, Carlo Di; Mattesini, Alessio.
Afiliação
  • Demola P; Structural Interventional Cardiology, Careggi University Hospital, Florence, Italy.
  • Meucci F; Structural Interventional Cardiology, Careggi University Hospital, Florence, Italy.
  • Stolcova M; Structural Interventional Cardiology, Careggi University Hospital, Florence, Italy.
  • Mario CD; Structural Interventional Cardiology, Careggi University Hospital, Florence, Italy.
  • Mattesini A; Structural Interventional Cardiology, Careggi University Hospital, Florence, Italy.
Future Cardiol ; 17(6): 945-951, 2021 09.
Article em En | MEDLINE | ID: mdl-33507091
A longtime aspiration of interventional cardiologists remains to improve the long-term impact of stent permanence in coronaries to restore original vessel patency and physiological endothelium response. Bioresorbable vascular scaffolds were considered revolutionary in coronary devices, but several trials were disappointing; thus, the challenge in this field remains. DESolve is a novolimus-eluting poly-L-lactide-based polymer scaffold that dissolves through a bio-reabsorption mechanism, vanishing completely in 2 years. Its ability to supply the necessary radial strength to support the vessel for the critical early months after delivery is an important feature showing a unique self-correction property, which reduces incomplete stent apposition. Overexpansion has a good, safe margin with DESolve. This review aims to provide an overview of this controversial topic.
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Doença da Artéria Coronariana / Intervenção Coronária Percutânea Limite: Humans Idioma: En Revista: Future Cardiol Assunto da revista: CARDIOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Itália

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Doença da Artéria Coronariana / Intervenção Coronária Percutânea Limite: Humans Idioma: En Revista: Future Cardiol Assunto da revista: CARDIOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Itália