Primary mediastinal large B-cell lymphoma in a patient on Fingolimod for relapsing-remitting multiple sclerosis.
Mult Scler Relat Disord
; 49: 102776, 2021 Apr.
Article
em En
| MEDLINE
| ID: mdl-33508568
ABSTRACT
BACKGROUND:
There are multiple case reports in the literature describing an association between fingolimod and cutaneous neoplasms.OBJECTIVE:
Investigate and report a case of a primary mediastinal large B-cell lymphoma in a patient on fingolimod for Relapsing-Remitting Multiple Sclerosis (RRMS).METHODS:
Case Report.RESULTS:
The patient developed a primary mediastinal large B-cell lymphoma after seven years of treatment with fingolimod. The patient is currently in complete remission after cessation of treatment, surgical resection, chemotherapy, and radiation therapy.CONCLUSION:
This case report highlights the first primary mediastinal large B-cell lymphoma associated with fingolimod treatment. It should be considered a rare, but potential adverse effect of fingolimod.Palavras-chave
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Linfoma de Células B
/
Esclerose Múltipla Recidivante-Remitente
/
Esclerose Múltipla
Limite:
Adult
/
Humans
Idioma:
En
Revista:
Mult Scler Relat Disord
Ano de publicação:
2021
Tipo de documento:
Article