Activation of Interferon Signaling in Chronic Lymphocytic Leukemia Cells Contributes to Apoptosis Resistance via a JAK-Src/STAT3/Mcl-1 Signaling Pathway.

Bauvois, Brigitte; Pramil, Elodie; Jondreville, Ludovic; Quiney, Claire; Nguyen-Khac, Florence; Susin, Santos A

Bauvois, Brigitte; Pramil, Elodie; Jondreville, Ludovic; Quiney, Claire; Nguyen-Khac, Florence; Susin, Santos A.

Afiliação

Bauvois B; Centre de Recherche des Cordeliers, INSERM, Cell Death and Drug Resistance in Lymphoproliferative Disorders Team, Sorbonne Université, Université Sorbonne Paris Cité, Université Paris Descartes, Université Paris Diderot, F-75006 Paris, France.
Pramil E; Centre de Recherche des Cordeliers, INSERM, Cell Death and Drug Resistance in Lymphoproliferative Disorders Team, Sorbonne Université, Université Sorbonne Paris Cité, Université Paris Descartes, Université Paris Diderot, F-75006 Paris, France.
Jondreville L; Centre de Recherche des Cordeliers, INSERM, Cell Death and Drug Resistance in Lymphoproliferative Disorders Team, Sorbonne Université, Université Sorbonne Paris Cité, Université Paris Descartes, Université Paris Diderot, F-75006 Paris, France.
Quiney C; Centre de Recherche des Cordeliers, INSERM, Cell Death and Drug Resistance in Lymphoproliferative Disorders Team, Sorbonne Université, Université Sorbonne Paris Cité, Université Paris Descartes, Université Paris Diderot, F-75006 Paris, France.
Nguyen-Khac F; Assistance Publique-Hôpitaux de Paris, Groupe Hospitalier Pitié-Salpêtrière, Service d'Hématologie Biologique, F-75013 Paris, France.
Susin SA; Centre de Recherche des Cordeliers, INSERM, Cell Death and Drug Resistance in Lymphoproliferative Disorders Team, Sorbonne Université, Université Sorbonne Paris Cité, Université Paris Descartes, Université Paris Diderot, F-75006 Paris, France.

Biomedicines ; 9(2)2021 Feb 13.

Article em En | MEDLINE | ID: mdl-33668421

Palavras-chave

CLL; IFN signaling; Mcl-1; STAT3; apoptosis; survival

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Texto completo: 1 Bases de dados: MEDLINE Idioma: En Revista: Biomedicines Ano de publicação: 2021 Tipo de documento: Article País de afiliação: França