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Synthesis, Optimization, and Biological Evaluation of Corrinated Conjugates of the GLP-1R Agonist Exendin-4.
Tinsley, Ian C; Borner, Tito; Swanson, MacKenzie L; Chepurny, Oleg G; Doebley, Sarah A; Kamat, Varun; Sweet, Ian R; Holz, George G; Hayes, Matthew R; De Jonghe, Bart C; Doyle, Robert P.
Afiliação
  • Tinsley IC; Department of Chemistry, Syracuse University, 111 College Place, Syracuse, New York 13244, United States.
  • Borner T; Department of Biobehavioral Health Sciences, University of Pennsylvania, School of Nursing, Philadelphia, Pennsylvania 19104, United States.
  • Swanson ML; Department of Chemistry, Syracuse University, 111 College Place, Syracuse, New York 13244, United States.
  • Chepurny OG; Department of Medicine, State University of New York, Upstate Medical University, Syracuse, New York 13210, United States.
  • Doebley SA; Department of Biobehavioral Health Sciences, University of Pennsylvania, School of Nursing, Philadelphia, Pennsylvania 19104, United States.
  • Kamat V; Department of Medicine, University of Washington, Medicine Diabetes Institute, Seattle, Washington 98109, United States.
  • Sweet IR; Department of Medicine, University of Washington, Medicine Diabetes Institute, Seattle, Washington 98109, United States.
  • Holz GG; Department of Medicine, State University of New York, Upstate Medical University, Syracuse, New York 13210, United States.
  • Hayes MR; Department of Psychiatry, University of Pennsylvania, Perelman School of Medicine, Philadelphia, Pennsylvania 19104, United States.
  • De Jonghe BC; Department of Biobehavioral Health Sciences, University of Pennsylvania, School of Nursing, Philadelphia, Pennsylvania 19104, United States.
  • Doyle RP; Department of Chemistry, Syracuse University, 111 College Place, Syracuse, New York 13244, United States.
J Med Chem ; 64(6): 3479-3492, 2021 03 25.
Article em En | MEDLINE | ID: mdl-33677970

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Corrinoides / Receptor do Peptídeo Semelhante ao Glucagon 1 / Exenatida Limite: Animals / Humans Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Corrinoides / Receptor do Peptídeo Semelhante ao Glucagon 1 / Exenatida Limite: Animals / Humans Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos