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Macrophage-specific responses to human- and animal-adapted tubercle bacilli reveal pathogen and host factors driving multinucleated cell formation.
Queval, Christophe J; Fearns, Antony; Botella, Laure; Smyth, Alicia; Schnettger, Laura; Mitermite, Morgane; Wooff, Esen; Villarreal-Ramos, Bernardo; Garcia-Jimenez, Waldo; Heunis, Tiaan; Trost, Matthias; Werling, Dirk; Salguero, Francisco J; Gordon, Stephen V; Gutierrez, Maximiliano G.
Afiliação
  • Queval CJ; The Francis Crick Institute, London, United Kingdom.
  • Fearns A; The Francis Crick Institute, London, United Kingdom.
  • Botella L; The Francis Crick Institute, London, United Kingdom.
  • Smyth A; UCD School of Veterinary Medicine and UCD Conway Institute, University College Dublin, Dublin, Ireland.
  • Schnettger L; The Francis Crick Institute, London, United Kingdom.
  • Mitermite M; UCD School of Veterinary Medicine and UCD Conway Institute, University College Dublin, Dublin, Ireland.
  • Wooff E; Animal and Plant Health Agency, Addlestone, United Kingdom.
  • Villarreal-Ramos B; Animal and Plant Health Agency, Addlestone, United Kingdom.
  • Garcia-Jimenez W; Institute of Biological, Environmental and Rural Sciences (IBERS), Aberystwyth University, Aberystwyth, United Kingdom.
  • Heunis T; Department of Pathology an Infectious Diseases. School of Veterinary Medicine. University of Surrey, Guildford, United Kingdom.
  • Trost M; Biosciences Institute, Newcastle University, Newcastle, United Kingdom.
  • Werling D; Biosciences Institute, Newcastle University, Newcastle, United Kingdom.
  • Salguero FJ; Department of Pathobiology and Population Sciences, The Royal Veterinary College, University of London, Hatfield Hertfordshire, United Kingdom.
  • Gordon SV; Department of Pathology an Infectious Diseases. School of Veterinary Medicine. University of Surrey, Guildford, United Kingdom.
  • Gutierrez MG; National Infection Service, Public Health England (PHE), Porton Down, Salisbury, United Kingdom.
PLoS Pathog ; 17(3): e1009410, 2021 03.
Article em En | MEDLINE | ID: mdl-33720986

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Tuberculose / Interações Hospedeiro-Patógeno / Tropismo Viral / Macrófagos / Mycobacterium bovis / Mycobacterium tuberculosis Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: PLoS Pathog Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Tuberculose / Interações Hospedeiro-Patógeno / Tropismo Viral / Macrófagos / Mycobacterium bovis / Mycobacterium tuberculosis Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: PLoS Pathog Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido