The safety and efficacy of metformin in fragile X syndrome: An open-label study.

Proteau-Lemieux, Mélodie; Lacroix, Angélina; Galarneau, Luc; Corbin, François; Lepage, Jean-François; Çaku, Artuela

Proteau-Lemieux, Mélodie; Lacroix, Angélina; Galarneau, Luc; Corbin, François; Lepage, Jean-François; Çaku, Artuela.

Afiliação

Proteau-Lemieux M; Sherbrooke University Hospital Research Center, Sherbrooke, Canada; Department of Pediatrics, Faculty of Medicine and Health Sciences, Sherbrooke University, Sherbrooke, Canada.
Lacroix A; Sherbrooke University Hospital Research Center, Sherbrooke, Canada; Department of Pharmacology, Faculty of Medicine and Health Sciences, Sherbrooke University, Sherbrooke, Canada.
Galarneau L; Sherbrooke University Hospital Research Center, Sherbrooke, Canada; Department of Biochemistry, Faculty of Medicine and Health Sciences, Sherbrooke University, Sherbrooke, Canada.
Corbin F; Sherbrooke University Hospital Research Center, Sherbrooke, Canada; Department of Biochemistry, Faculty of Medicine and Health Sciences, Sherbrooke University, Sherbrooke, Canada.
Lepage JF; Sherbrooke University Hospital Research Center, Sherbrooke, Canada; Department of Pediatrics, Faculty of Medicine and Health Sciences, Sherbrooke University, Sherbrooke, Canada. Electronic address: jean-francois.lepage@usherbrooke.ca.
Çaku A; Sherbrooke University Hospital Research Center, Sherbrooke, Canada; Department of Biochemistry, Faculty of Medicine and Health Sciences, Sherbrooke University, Sherbrooke, Canada.

Prog Neuropsychopharmacol Biol Psychiatry ; 110: 110307, 2021 08 30.

Article em En | MEDLINE | ID: mdl-33757860

Assuntos

Potencial Evocado Motor/efeitos dos fármacos; Síndrome do Cromossomo X Frágil/tratamento farmacológico; Síndrome do Cromossomo X Frágil/fisiopatologia; Hipoglicemiantes/uso terapêutico; Metformina/uso terapêutico; Estimulação Magnética Transcraniana/métodos; Adolescente; Adulto; Potencial Evocado Motor/fisiologia; Feminino; Síndrome do Cromossomo X Frágil/psicologia; Humanos; Hipoglicemiantes/farmacologia; Masculino; Metformina/farmacologia; Córtex Motor/efeitos dos fármacos; Córtex Motor/fisiologia; Testes Neuropsicológicos; Resultado do Tratamento; Adulto Jovem

Palavras-chave

Behavior; Cognition; Cortical excitability; Fragile X syndrome; Inhibitory mechanisms; Metformin

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Potencial Evocado Motor / Estimulação Magnética Transcraniana / Síndrome do Cromossomo X Frágil / Hipoglicemiantes / Metformina Limite: Adolescent / Adult / Female / Humans / Male Idioma: En Revista: Prog Neuropsychopharmacol Biol Psychiatry Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Canadá

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